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SULT1E1
Gene Name
sulfotransferase family 1E, estrogen-preferring, member 1
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Estrone Sulfotransferase Activity
Steroid Binding
Flavonol 3-sulfotransferase Activity
Steroid Sulfotransferase Activity
Biological Process
Xenobiotic Metabolic Process
Female Pregnancy
Steroid Metabolic Process
Estrogen Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Sulfation
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Cytosolic sulfonation of small molecules
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Cyclizine
Adenosine-3\'-5\'-Diphosphate
3\'-Phosphate-Adenosine-5\'-Phosphate Sulfate
3,5,3\',5\'-Tetrachloro-Biphenyl-4,4\'-Diol
Diseases
GWAS
Protein-protein Interactions
13 interactors:
BMPR2
C14orf1
COPS6
EEF1A1
ENOX1
IGSF21
LRIF1
PDE9A
RBM48
SETDB1
SULT2B1
TP53
UNC119
Entrez ID
6783
HPRD ID
08966
Ensembl ID
ENSG00000109193
Uniprot IDs
P49888
Q53X91
PDB IDs
1G3M
1HY3
4JVL
4JVM
4JVN
Enriched GO Terms of Interacting Partners
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analyzing
bovine
caruncular
catalyzed
conflict
conflicting
esr
esrs
estrogens
expresses
giant
placentas
pools
posttranscriptional
produces
resolve
sorting
sulfonation
tgc
tgcs
transcript
trophoblast
unable
uninucleated
utc
utcs
virtually