ACE2

Gene Name		angiotensin I converting enzyme 2
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Virus Receptor Activity Glycoprotein Binding Endopeptidase Activity Carboxypeptidase Activity Protein Binding Metallopeptidase Activity Peptidyl-dipeptidase Activity Zinc Ion Binding Peptide Hormone Binding
	Biological Process	Regulation Of Cytokine Production Angiotensin Maturation Angiotensin Catabolic Process In Blood Angiotensin-mediated Drinking Behavior Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Proteolysis Response To Virus Regulation Of Vasoconstriction Receptor Biosynthetic Process Regulation Of Cell Proliferation Regulation Of Vasodilation Cellular Protein Metabolic Process Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Regulation Of Inflammatory Response Maternal Process Involved In Female Pregnancy Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways		Peptide hormone metabolism Metabolism of Angiotensinogen to Angiotensins
Drugs		Moexipril Lisinopril
Diseases
GWAS
Protein-protein Interactions		3 interactors: AGT GHRL NTS
Entrez ID		59272
HPRD ID		02274
Ensembl ID		ENSG00000130234
Uniprot IDs		Q9BYF1
PDB IDs		1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Multicellular Organism Growth Regulation Of Protein Tyrosine Kinase Activity Regulation Of Blood Vessel Size Regulation Of Tube Size Negative Regulation Of Angiogenesis Feeding Behavior Regulation Of Multicellular Organism Growth Uterine Smooth Muscle Contraction Cortisol Secretion Angiotensin Mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Developmental Growth Regulation Of Peptidyl-tyrosine Phosphorylation Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Positive Regulation Of Protein Kinase C Activity Catenin Import Into Nucleus Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Regulation Of Angiogenesis Positive Regulation Of Growth Female Pregnancy Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Angiotensin-mediated Drinking Behavior Smooth Muscle Cell Proliferation Positive Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation Of NAD(P)H Oxidase Activity Positive Regulation Of Extracellular Matrix Constituent Secretion G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Ovarian Follicle Rupture Regulation Of Renal Output By Angiotensin Regulation Of Hormone Levels Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Inflammatory Response Regulation Of Developmental Growth Positive Regulation Of Appetite Positive Regulation Of Cortisol Secretion Positive Regulation Of Corticotropin Secretion Fibroblast Proliferation Astrocyte Activation Renin-angiotensin Regulation Of Aldosterone Production Blood Circulation Positive Regulation Of Secretion Regulation Of Corticotropin Secretion Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Blood Vessel Size By Renin-angiotensin Negative Regulation Of Interleukin-6 Biosynthetic Process Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Tagcloud ?		aav adeno blunt blunted blunts bp contribution cre doca floxed gfp hace2 harboring hypertension icv infused neurogenic nt paraventricular pvn recombinase salt sfo sham sl subfornical transgene transgenic tudca