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SMG9

Gene Name SMG9 nonsense mediated mRNA decay factor
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Intracellular
  • Cytosol
Molecular Function
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
  • Gene Expression
Pathways
  • Nonsense-Mediated Decay (NMD)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-protein Interactions 3 interactors: KRT31 TRAF2 TRIM23
Entrez ID 56006
HPRD ID 07800
Ensembl ID ENSG00000105771
Uniprot IDs Q9H0W8
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Negative Regulation Of Glial Cell Apoptotic Process
  • Positive Regulation Of Protein Homodimerization Activity
  • Cellular Response To Nitric Oxide
  • Regulation Of Immunoglobulin Secretion
  • Response To Nitric Oxide
  • Protein Ubiquitination
  • Protein Modification By Small Protein Conjugation
  • Positive Regulation Of T Cell Cytokine Production
  • Protein Homotrimerization
  • Regulation Of Protein Homodimerization Activity
  • Cellular Response To Reactive Nitrogen Species
  • Regulation Of T Cell Cytokine Production
  • Activation Of NF-kappaB-inducing Kinase Activity
  • Positive Regulation Of NIK/NF-kappaB Signaling
  • Protein K63-linked Ubiquitination
  • Tumor Necrosis Factor-mediated Signaling Pathway
  • Protein Trimerization
  • Positive Regulation Of Interleukin-2 Production
  • NIK/NF-kappaB Signaling
  • Regulation Of NIK/NF-kappaB Signaling
  • Protein Autoubiquitination
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