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PPAT

Gene Name phosphoribosyl pyrophosphate amidotransferase
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Cytosol
Molecular Function
  • Amidophosphoribosyltransferase Activity
  • Metal Ion Binding
  • 4 Iron, 4 Sulfur Cluster Binding
Biological Process
  • G1/S Transition Of Mitotic Cell Cycle
  • Kidney Development
  • Purine Nucleobase Metabolic Process
  • Purine Nucleotide Biosynthetic Process
  • 'de Novo' IMP Biosynthetic Process
  • Glutamine Catabolic Process
  • Lactation
  • Purine Nucleobase Biosynthetic Process
  • Nucleoside Metabolic Process
  • Purine Ribonucleoside Monophosphate Biosynthetic Process
  • Organ Regeneration
  • Cellular Response To Insulin Stimulus
  • Cellular Response To Drug
  • Small Molecule Metabolic Process
  • Protein Homotetramerization
  • Nucleobase-containing Small Molecule Metabolic Process
  • Maternal Process Involved In Female Pregnancy
Pathways
  • Purine ribonucleoside monophosphate biosynthesis
  • Purine metabolism
  • Metabolism of nucleotides
Drugs
  • L-Glutamine
Diseases
GWAS
Protein-protein Interactions 2 interactors: ATXN1 EPT1
Entrez ID 5471
HPRD ID 01402
Ensembl ID ENSG00000128059
Uniprot IDs A8K4H7 Q06203 Q59G63
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
  • Phosphatidylethanolamine Biosynthetic Process
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© Madhavi K. Ganapathiraju 2012-2025