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PLCB4

Gene Name phospholipase C, beta 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Nucleus
  • Smooth Endoplasmic Reticulum
  • Cytosol
  • Postsynaptic Density
  • Dendrite
Molecular Function
  • Phosphatidylinositol Phospholipase C Activity
  • Phospholipase C Activity
  • Signal Transducer Activity
  • Calcium Ion Binding
Biological Process
  • Lipid Catabolic Process
  • Intracellular Signal Transduction
  • Inositol Phosphate Metabolic Process
  • Small Molecule Metabolic Process
Pathways
  • G alpha (q) signalling events
  • G alpha (q) signalling events
  • Signaling by GPCR
  • GPCR downstream signaling
  • Synthesis of IP3 and IP4 in the cytosol
  • PLC beta mediated events
  • Gastrin-CREB signalling pathway via PKC and MAPK
  • Opioid Signalling
  • G-protein mediated events
  • Inositol phosphate metabolism
Drugs
Diseases
GWAS
  • Neutrophil count ( 20172861)
Protein-protein Interactions 1 interactors: REL
Entrez ID 5332
HPRD ID 02885
Ensembl ID ENSG00000101333
Uniprot IDs Q15147 Q5JYS9
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Positive Regulation Of Interleukin-12 Biosynthetic Process
  • Regulation Of Interleukin-12 Biosynthetic Process
  • NIK/NF-kappaB Signaling
  • Positive Regulation Of Interleukin-12 Production
  • I-kappaB Kinase/NF-kappaB Signaling
  • Regulation Of Interleukin-12 Production
  • Positive Regulation Of Cytokine Biosynthetic Process
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© Madhavi K. Ganapathiraju 2012-2025