PCK2

Gene Name		phosphoenolpyruvate carboxykinase 2 (mitochondrial)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Phosphoenolpyruvate Carboxykinase Activity Phosphoenolpyruvate Carboxykinase (GTP) Activity Protein Binding GTP Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Pyruvate Metabolic Process Gluconeogenesis Oxaloacetate Metabolic Process NADH Oxidation Pathogenesis Positive Regulation Of Insulin Secretion Small Molecule Metabolic Process Response To Glucocorticoid Cellular Response To Glucose Stimulus
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP EP300 SMAD3
Entrez ID		5106
HPRD ID		02026
Ensembl ID		ENSG00000100889
Uniprot IDs		B4DW73 Q16822
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Binding Posttranscriptional Regulation Of Gene Expression Somitogenesis Protein Stabilization Somite Development Regulation Of Cell Cycle Segmentation Apoptotic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Regulation Of Protein Stability Response To Abiotic Stimulus Notch Signaling Pathway Positive Regulation Of Peptidase Activity Regulation Of Protein Binding Histone H2B Acetylation Positive Regulation Of Transforming Growth Factor Beta3 Production Immune Response Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Anterior/posterior Pattern Specification N-terminal Peptidyl-lysine Acetylation Collateral Sprouting In Absence Of Injury Evasion Or Tolerance Of Host Defenses By Virus Developmental Growth Positive Regulation Of Proteolysis Response To Hypoxia Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tubulin Deacetylation Regulation Of Extracellular Matrix Assembly Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cellular Protein Metabolic Process Apoptotic Signaling Pathway Positive Regulation Of Cytokine Production Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Primary MiRNA Processing Negative Regulation Of Cellular Metabolic Process Regulation Of Endopeptidase Activity Immune System Process Axon Choice Point Recognition Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Tagcloud ?		aar adjoins atf atf4 carboxykinase eif2alpha flux gcn2 gluconeogenesis gluconeogenic glutamine glycolytic inducers intermediates limitation links mcf7 origins oxaloacetate pepck phosphoenolpyruvate pools potentiating profusely shed tca tumorigenic unexpected upr