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PAX4

Gene Name paired box 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Nucleoplasm
Molecular Function
  • RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
  • RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
  • DNA Binding
  • Double-stranded DNA Binding
Biological Process
  • Negative Regulation Of Transcription From RNA Polymerase II Promoter
  • Transcription, DNA-templated
  • Circadian Rhythm
  • Organ Morphogenesis
  • Cell Differentiation
  • Endocrine Pancreas Development
  • Response To Drug
  • Negative Regulation Of Apoptotic Process
  • Positive Regulation Of Cell Differentiation
  • Response To CAMP
  • Retina Development In Camera-type Eye
Pathways
  • Regulation of beta-cell development
  • Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
Drugs
Diseases
GWAS
  • Type 2 diabetes ( 22158537 23532257)
Protein-protein Interactions 1 interactors: GMCL1
Entrez ID 5078
HPRD ID 01333
Ensembl ID ENSG00000106331
Uniprot IDs O43316
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025