POLN

Gene Name		polymerase (DNA directed) nu
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Cyclin Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA-dependent DNA Replication Translesion Synthesis Interstrand Cross-link Repair
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease ( 22159054)
Protein-protein Interactions		2 interactors: ATR POLDIP2
Entrez ID		353497
HPRD ID		17876
Ensembl ID		ENSG00000130997
Uniprot IDs		Q7Z5Q5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Signal Transduction By P53 Class Mediator Replicative Senescence Cellular Response To Gamma Radiation Mitochondrion Morphogenesis Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Response To Heat Substrate Adhesion-dependent Cell Spreading Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Replication Response To Gamma Radiation Cellular Response To Ionizing Radiation Cellular Response To UV Cellular Response To Heat Positive Regulation Of Response To DNA Damage Stimulus Actin Cytoskeleton Reorganization Cell Aging Double-strand Break Repair Via Homologous Recombination Recombinational Repair
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