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HIST1H1B
Gene Name
histone cluster 1, H1b
Image
Gene Ontology Annotations
Cellular Component
Nucleosome
Nuclear Chromatin
Nuclear Heterochromatin
Extracellular Vesicular Exosome
Molecular Function
Chromatin DNA Binding
Histone Deacetylase Binding
Poly(A) RNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Nucleosome Assembly
Positive Regulation Of Cell Growth
Protein Stabilization
Positive Regulation Of Histone H3-K9 Methylation
Establishment Of Protein Localization To Chromatin
Pathways
DNA Damage/Telomere Stress Induced Senescence
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Activation of DNA fragmentation factor
Apoptosis induced DNA fragmentation
Cellular Senescence
Programmed Cell Death
Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-protein Interactions
26 interactors:
CBX5
CCNA1
CCNA2
CCNB1
CCNE1
CDK1
CDK2
CDK5
CDKN1A
CDKN1B
EHMT2
IRAK4
KAT2A
KAT2B
L3MBTL1
LOX
MELK
MLLT1
NSD1
PRKCA
PRKCB
PRKCD
PRKCZ
RPS6KA5
SERPINH1
SIRT1
Entrez ID
3009
HPRD ID
00821
Ensembl ID
ENSG00000184357
Uniprot IDs
P16401
PDB IDs
2FE2
2RHI
Enriched GO Terms of Interacting Partners
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Regulation Of Protein Kinase Activity
Regulation Of Kinase Activity
Regulation Of Protein Phosphorylation
Histone Modification
Peptidyl-amino Acid Modification
Chromatin Modification
Regulation Of Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Cell Cycle
Regulation Of Cell Cycle
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Metabolic Process
Chromatin Organization
Histone Phosphorylation
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Nitrogen Compound Metabolic Process
Cellular Protein Modification Process
Regulation Of Mitotic Cell Cycle
Cell Cycle Process
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Cellular Metabolic Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle Process
Regulation Of Gene Expression
Mitotic Cell Cycle
Chromosome Organization
Regulation Of Catalytic Activity
Negative Regulation Of Phosphorylation
Protein Phosphorylation
G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Cellular Protein Metabolic Process
Response To Stress
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Protein Metabolic Process
Protein Metabolic Process
Response To Wounding
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Cellular Protein Metabolic Process
Peptidyl-threonine Phosphorylation
Peptidyl-serine Phosphorylation
Regulation Of RNA Metabolic Process
Negative Regulation Of Protein Kinase Activity
Regulation Of Metabolic Process
Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of Kinase Activity
Positive Regulation Of Cell Proliferation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Wound Healing
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