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SULT4A1
Gene Name
sulfotransferase family 4A, member 1
Image
Gene Ontology Annotations
Cellular Component
Cytosol
Molecular Function
Protein Binding
Sulfotransferase Activity
Biological Process
Xenobiotic Metabolic Process
Biological_process
Steroid Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Cytosolic sulfonation of small molecules
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Type 2 diabetes (dietary heme iron intake interaction) (
23386860
)
Protein-protein Interactions
1 interactors:
POT1
Entrez ID
25830
HPRD ID
07462
Ensembl ID
ENSG00000130540
Uniprot IDs
B7Z2E1
Q9BR01
PDB IDs
1ZD1
Enriched GO Terms of Interacting Partners
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Positive Regulation Of DNA Strand Elongation
Telomere Formation Via Telomerase
Positive Regulation Of Helicase Activity
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Positive Regulation Of Telomerase Activity
Telomere Assembly
Positive Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomerase Activity
Regulation Of Telomere Maintenance
Positive Regulation Of DNA Biosynthetic Process
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Regulation Of DNA Biosynthetic Process
Negative Regulation Of DNA Replication
Positive Regulation Of DNA Replication
Telomere Maintenance
DNA Duplex Unwinding
DNA Geometric Change
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Metabolic Process
Regulation Of DNA Replication
Positive Regulation Of DNA Metabolic Process
Regulation Of Chromosome Organization
DNA Replication
DNA Conformation Change
Negative Regulation Of Transferase Activity
Positive Regulation Of Organelle Organization
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