FAM21C

Gene Name		family with sequence similarity 21, member C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane Early Endosome Membrane WASH Complex
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Regulation Of Substrate Adhesion-dependent Cell Spreading Retrograde Transport, Endosome To Plasma Membrane Negative Regulation Of Barbed-end Actin Filament Capping
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-protein Interactions		4 interactors: ATXN1 FKBP15 KIAA0196 VPS35
Entrez ID		253725
HPRD ID		11094
Ensembl ID		ENSG00000172661
Uniprot IDs		A8K5W5 B3KMC4 Q9Y4E1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Late Endosome To Lysosome Transport Endosomal Transport Intracellular Transport Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Retrograde Transport, Endosome To Plasma Membrane Transport Transcytosis Establishment Of Localization In Cell Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Localization
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