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SEC11A

Gene Name SEC11 homolog A (S. cerevisiae)
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Endoplasmic Reticulum Membrane
  • Integral Component Of Membrane
  • Extracellular Vesicular Exosome
Molecular Function
  • Serine-type Peptidase Activity
Biological Process
  • Translation
  • Signal Peptide Processing
  • Proteolysis
  • SRP-dependent Cotranslational Protein Targeting To Membrane
  • Gene Expression
  • Cellular Protein Metabolic Process
  • Regulation Of Insulin Secretion
Pathways
  • Peptide hormone metabolism
  • Synthesis, secretion, and deacylation of Ghrelin
  • Translation
  • Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
  • SRP-dependent cotranslational protein targeting to membrane
  • Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
  • Incretin synthesis, secretion, and inactivation
Drugs
Diseases
GWAS
Protein-protein Interactions 3 interactors: CSNK2B NUPR1 SLC35F6
Entrez ID 23478
HPRD ID 07503
Ensembl ID ENSG00000140612
Uniprot IDs B4DUL4 H0YK72 H0YK83 H0YKT4 P67812
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Regulation Of Cell Proliferation
  • Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
  • Positive Regulation Of Activin Receptor Signaling Pathway
  • Adiponectin-activated Signaling Pathway
  • Endothelial Tube Morphogenesis
  • Regulation Of Female Gonad Development
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