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ARHGEF15
Gene Name
Rho guanine nucleotide exchange factor (GEF) 15
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Dendrite
Molecular Function
Rho Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Biological Process
Positive Regulation Of Rho GTPase Activity
Regulation Of Catalytic Activity
Positive Regulation Of Stress Fiber Assembly
Retina Vasculature Morphogenesis In Camera-type Eye
Negative Regulation Of Synapse Maturation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
8 interactors:
C11orf49
CEP55
EPHA4
ESR1
ESRRG
LASP1
MOB4
PIN1
Entrez ID
22899
HPRD ID
10535
Ensembl ID
ENSG00000198844
Uniprot IDs
O94989
PDB IDs
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity
Steroid Hormone Mediated Signaling Pathway
Fasciculation Of Motor Neuron Axon
Hormone-mediated Signaling Pathway
Fasciculation Of Sensory Neuron Axon
Prostate Epithelial Cord Elongation
Transcription Initiation From RNA Polymerase II Promoter
Cellular Response To Steroid Hormone Stimulus
Negative Regulation Of Axon Regeneration
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Intracellular Receptor Signaling Pathway
Branch Elongation Involved In Mammary Gland Duct Branching
Antral Ovarian Follicle Growth
DNA-templated Transcription, Initiation
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Branching Involved In Pregnancy
Regulation Of Rho GTPase Activity
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Rho Protein Signal Transduction
Corticospinal Tract Morphogenesis
Vagina Development
Positive Regulation Of Signal Transduction
Regulation Of Axon Regeneration
Uterus Development
Regulation Of Signal Transduction
Cellular Response To Organic Cyclic Compound
Intracellular Estrogen Receptor Signaling Pathway
Positive Regulation Of Nitric-oxide Synthase Activity
Cell Separation After Cytokinesis
Regulation Of Rap GTPase Activity
Cellular Response To Estradiol Stimulus
Prostate Gland Growth
Regulation Of Rac GTPase Activity
Branching Involved In Prostate Gland Morphogenesis
Negative Regulation Of Intracellular Signal Transduction
Cellular Response To Lipid
Mammary Gland Epithelial Cell Proliferation
Female Genitalia Development
Axonal Fasciculation
Regulation Of Rap Protein Signal Transduction
Regulation Of Signaling
Positive Regulation Of Monooxygenase Activity
Branch Elongation Of An Epithelium
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