PHACTR1

Gene Name		phosphatase and actin regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Cell Junction Synapse
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Phosphatase 1 Binding Protein Phosphatase Type 1 Regulator Activity
	Biological Process	Actomyosin Structure Organization Actin Cytoskeleton Reorganization Negative Regulation Of Catalytic Activity Stress Fiber Assembly Cell Motility
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 22763476) Coronary artery calcification ( 22144573) Coronary heart disease ( 22745674 21846871 22751097 21378988 21378990) Hip geometry ( 17903296) Migraine ( 22683712) Myocardial infarction (early onset) ( 19198609)
Protein-protein Interactions		2 interactors: ACTA1 PPP1CA
Entrez ID		221692
HPRD ID		12283
Ensembl ID
Uniprot IDs		Q9C0D0
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Fiber Adaptation Skeletal Muscle Thin Filament Assembly Skeletal Myofibril Assembly Regulation Of Glycogen Catabolic Process Skeletal Muscle Adaptation Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Skeletal Muscle Fiber Development Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Response To Abiotic Stimulus Myotube Cell Development Response To Lithium Ion Regulation Of Glycogen Biosynthetic Process Muscle Filament Sliding Actin-myosin Filament Sliding Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Glycogen Metabolic Process Actin-mediated Cell Contraction Muscle Fiber Development Myotube Differentiation Glycogen Metabolic Process Actin Filament-based Movement Tissue Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To External Stimulus Regulation Of Generation Of Precursor Metabolites And Energy Myofibril Assembly Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Triglyceride Metabolic Process Regulation Of Circadian Rhythm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Glucose Metabolic Process Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Actomyosin Structure Organization Anatomical Structure Morphogenesis Response To Organic Substance Energy Reserve Metabolic Process Skeletal Muscle Tissue Development Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Lipid Catabolic Process Skeletal Muscle Organ Development Cell Growth Regulation Of Carbohydrate Metabolic Process
Tagcloud ?		actin attribute basic beta1 ccg depleted emt follows import importin mal mkl1 monomeric motifs mrtf msenchymal myocardin nb nls nlss pool prevents proposal proximity pull rho rpel sepharose vital