DHCR24

Gene Name		24-dehydrocholesterol reductase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Membrane Integral Component Of Membrane
	Molecular Function	Delta24(24-1) Sterol Reductase Activity UDP-N-acetylmuramate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor Enzyme Binding Peptide Antigen Binding Delta24-sterol Reductase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Cholesterol Biosynthetic Process Apoptotic Process Response To Oxidative Stress Cell Cycle Arrest Ras Protein Signal Transduction Protein Localization Negative Regulation Of Cell Proliferation Response To Hormone Tissue Development Male Genitalia Development Plasminogen Activation Amyloid Precursor Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Skin Development Small Molecule Metabolic Process Oxidation-reduction Process Membrane Organization Regulation Of Neuron Death
Pathways		Cholesterol biosynthesis Metabolism of lipids and lipoproteins
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: TP53
Entrez ID		1718
HPRD ID		05916
Ensembl ID		ENSG00000116133
Uniprot IDs		B7Z817 Q15392
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Negative Regulation Of Helicase Activity Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Mitochondrial DNA Repair Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Thymocyte Apoptotic Process Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Rhythmic Behavior Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Protein Oligomerization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process RRNA Transcription T Cell Lineage Commitment Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Entrainment Of Circadian Clock By Photoperiod Positive Regulation Of Protein Deacetylation Cellular Response To Glucose Starvation Positive Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Neuroblast Proliferation Photoperiodism Entrainment Of Circadian Clock Protein Import Into Nucleus, Translocation Regulation Of Protein Oligomerization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitochondrial Genome Maintenance Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Necroptotic Process Response To X-ray
Tagcloud ?		3beta accumulating adenovirus bip caveolae caveolin chop colocalization delta24 hydroxysteroid infected lacz microdomain multifunctional n2a neuroblastoma neuroprotective organized perk possesses protect reductase serving stronger synthesizing tagged tm tunicamycin weaker