AP1S3

Gene Name		adaptor-related protein complex 1, sigma 3 subunit
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Cytosol Coated Pit Membrane Coat Cytoplasmic Vesicle Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Transporter Activity
	Biological Process	Protein Targeting Post-Golgi Vesicle-mediated Transport Viral Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Regulation Of Defense Response To Virus By Virus Membrane Organization
Pathways		Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters HIV Infection Host Interactions of HIV factors Golgi Associated Vesicle Biogenesis The role of Nef in HIV-1 replication and disease pathogenesis Nef mediated downregulation of MHC class I complex cell surface expression Clathrin derived vesicle budding Lysosome Vesicle Biogenesis MHC class II antigen presentation trans-Golgi Network Vesicle Budding Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: AAGAB PRKAG1
Entrez ID		130340
HPRD ID		16495
Ensembl ID		ENSG00000152056
Uniprot IDs		Q96PC3
PDB IDs		4HMY
Enriched GO Terms of Interacting Partners?
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