IQGAP3

Gene Name		IQ motif containing GTPase activating protein 3
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cell-cell Junction Lateral Plasma Membrane
	Molecular Function	Ras GTPase Activator Activity Calmodulin Binding Rho GTPase Binding Myosin VI Light Chain Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Activation Of MAPK Activity Ras Protein Signal Transduction Regulation Of Cell Size Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Ras GTPase Activity Positive Regulation Of Mammary Gland Epithelial Cell Proliferation ERK1 And ERK2 Cascade Cellular Response To Organic Substance
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: CALM2
Entrez ID		128239
HPRD ID		11051
Ensembl ID		ENSG00000183856
Uniprot IDs		Q86VI3
PDB IDs		3ISU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Dephosphorylation Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Nitric Oxide Metabolic Process Activation Of Adenylate Cyclase Activity Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Positive Regulation Of Cation Channel Activity Response To Amphetamine Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Adenylate Cyclase Activity Regulation Of Nitric-oxide Synthase Activity Substantia Nigra Development Response To Mineralocorticoid Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Transporter Activity Negative Regulation Of Calcium Ion Transport Positive Regulation Of Lyase Activity Positive Regulation Of Dephosphorylation Negative Regulation Of Ion Transmembrane Transport Response To Amine Inositol Phosphate Metabolic Process Activation Of Phospholipase C Activity Positive Regulation Of Ion Transmembrane Transporter Activity
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