METTL23

Description		methyltransferase 23, arginine
Image		No pdb structure
GO Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Protein Binding Methyltransferase Activity Transferase Activity Heat Shock Protein Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H3R17 Methyltransferase Activity DNA-binding Transcription Factor Binding
	Biological Process	Chromatin Organization Regulation Of Gene Expression Methylation Epigenetic Regulation Of Gene Expression Epigenetic Programming In The Zygotic Pronuclei Epigenetic Programing Of Male Pronucleus Positive Regulation Of Transcription By RNA Polymerase II Cognition
Pathways		Chromatin modifications during the maternal to zygotic transition (MZT) Replacement of protamines by nucleosomes in the male pronucleus
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: BCL2L1 TK1
Entrez ID		124512
HPRD ID		19210
Ensembl ID		ENSG00000181038
Uniprot IDs		Q86XA0 Q8N712
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Cycloheximide Bcl-2 Family Protein Complex Negative Regulation Of Dendritic Cell Apoptotic Process Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Apoptotic Process In Bone Marrow Cell BH3 Domain Binding Negative Regulation Of Execution Phase Of Apoptosis DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Deoxyribonucleoside Monophosphate Biosynthetic Process Thymidine Kinase Activity Pyrimidine Nucleoside Metabolic Process Hepatocyte Apoptotic Process Negative Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Release Of Cytochrome C From Mitochondria Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Membrane Permeability Negative Regulation Of Anoikis Programmed Cell Death Involved In Cell Development Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Anoikis Cellular Response To Gamma Radiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Cellular Response To Alkaloid Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Channel Activity Pyrimidine-containing Compound Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Regulation Of Release Of Cytochrome C From Mitochondria Leukocyte Apoptotic Process Epithelial Cell Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Ovarian Follicle Development Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleoside Metabolic Process Negative Regulation Of Response To Endoplasmic Reticulum Stress Response To Gamma Radiation Negative Regulation Of Leukocyte Apoptotic Process Regulation Of Mitochondrial Membrane Permeability Protein Homotetramerization Apoptotic Mitochondrial Changes See more
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