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PTPMT1

Gene Name protein tyrosine phosphatase, mitochondrial 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
  • Nucleus
  • Mitochondrion
  • Integral Component Of Mitochondrial Inner Membrane
Molecular Function
  • Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity
  • Protein Tyrosine Phosphatase Activity
  • Protein Tyrosine/serine/threonine Phosphatase Activity
  • Phosphatidylglycerophosphatase Activity
Biological Process
  • Protein Dephosphorylation
  • Phospholipid Metabolic Process
  • Phosphatidylglycerol Biosynthetic Process
  • Cardiolipin Biosynthetic Process
  • Peptidyl-tyrosine Dephosphorylation
  • Small Molecule Metabolic Process
  • Glycerophospholipid Biosynthetic Process
  • Inositol Phosphate Dephosphorylation
Pathways
  • Metabolism of lipids and lipoproteins
  • Synthesis of PG
  • Phospholipid metabolism
  • Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-protein Interactions 16 interactors: KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP2-4 KRTAP5-9 KRTAP9-2 MAPK6 MDFI MTUS2 NOTCH2NL RGS20 SIAH1 TAB1 TRIM27
Entrez ID 114971
HPRD ID 15151
Ensembl ID
Uniprot IDs Q8WUK0
PDB IDs
Enriched GO Terms of Interacting Partners?
  • MAPK Cascade
  • Signal Transduction By Phosphorylation
  • JNK Cascade
  • Negative Regulation Of Interleukin-2 Secretion
  • Stress-activated MAPK Cascade
  • Stress-activated Protein Kinase Signaling Cascade
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© Madhavi K. Ganapathiraju 2012-2025