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ZNF655 and EXOSC5
Data Source:
BioGRID
(two hybrid)
ZNF655
EXOSC5
Description
zinc finger protein 655
exosome component 5
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Nuclear Exosome (RNase Complex)
Cytoplasmic Exosome (RNase Complex)
Exosome (RNase Complex)
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Transcriptionally Active Chromatin
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Molecular_function
Protein Binding
Metal Ion Binding
3'-5'-exoribonuclease Activity
RNA Binding
Exoribonuclease Activity
Protein Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
RRNA Processing
RRNA Catabolic Process
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic, 3'-5'
U4 SnRNA 3'-end Processing
Regulation Of MRNA Stability
Exonucleolytic Catabolism Of Deadenylated MRNA
DNA Deamination
Defense Response To Virus
Nuclear MRNA Surveillance
Polyadenylation-dependent SnoRNA 3'-end Processing
RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways
Generic Transcription Pathway
ATF4 activates genes in response to endoplasmic reticulum stress
mRNA decay by 3' to 5' exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS
Serum metabolite levels (
23093944
)
Interacting Genes
155 interacting genes:
ACSL6
ANKRD11
AP1M1
ASB6
ASMTL
ATPAF2
BARD1
BORCS6
BYSL
C8orf34
C8orf74
CAPN7
CARD9
CBY2
CCDC116
CCDC179
CCDC57
CCDC74A
CCHCR1
CCNH
CDC37
CDK4
CDR2L
CEP57L1
CPNE7
CRACR2A
CWF19L2
DBF4B
DEUP1
DPF2
DUSP4
EGLN3
EIF4EBP1
EMILIN1
EVL
EXOSC5
FADS2
FAM214B
FAM81A
FAM81B
FAM90A1
FARS2
FHL2
FKBP6
GEM
GFAP
GSTP1
GUCD1
HAPLN2
HEXIM2
HOMER3
HOOK1
HOXB5
HPCAL1
HSD3B7
HTT
IDI1
IMP3
INTS10
INTS13
IP6K3
ITGB5
JRK
KIFC3
KRT40
KRT76
KRT85
KRT86
KRTAP4-12
KRTAP5-9
KRTAP9-8
LCE3C
LCE4A
LCE5A
LGALS14
LMO2
LNX1
LRRC29
MACO1
MAD2L2
MAGEA11
MAGEA2B
MBD3
MED21
MEMO1
METTL21A
MIS18A
MITD1
MPP3
MRFAP1
MRPL28
MTMR9
MTUS2
MXI1
NAA10
NDC80
NECAB2
NGB
NOTUM
NUDT21
NUDT22
NXT2
OIP5
OSTF1
OTUD4
P2RX7
PBX3
PCSK5
PFKFB1
POLR1C
PRR35
RIN3
RINT1
RRM1
RUNX1T1
SH2D4A
SIGLEC6
SLC12A4
SMARCD1
SMG9
SPANXN2
SPRED1
SPRY3
SRGAP2B
SZT2
TCEANC
TEKT4
TEX28
THAP6
TIMM10
TLK1
TNS2
TRAF2
TRAF5
TRAPPC2
TRAPPC2B
TRIM37
TRIM41
TRIM72
TRIP13
TSPYL4
TXNDC9
USHBP1
VAV1
VPS26C
VPS9D1
XPA
YPEL5
ZBTB16
ZC2HC1C
ZNF330
ZNF552
ZNF648
ZNF792
ZNF837
80 interacting genes:
ACOT11
ADAMTSL4
BIRC2
BORCS6
CALCOCO2
CCDC88B
CDK5RAP1
DAAM2
DDIT4L
DHRS2
DIS3
DMRTB1
DOCK8
EFHC2
EXOSC1
EXOSC10
EXOSC2
EXOSC3
EXOSC6
EXOSC7
EXOSC8
EXOSC9
FCHO1
FH
FHL3
GOLGA2
HBS1L
HOXC4
IKZF3
KCTD13
KIAA1217
KRT13
KRT27
KRT31
KRT34
KRT35
LCA5L
LIPG
LRMDA
LSM3
LSM5
LZTS2
MEOX2
MPHOSPH6
MTMR3
MTREX
MYLIP
NKAPD1
NMI
NUP210
PA2G4
PALS2
PEG10
PICK1
PIH1D2
PKM
POLR2L
PRDM6
PTEN
REL
SFPQ
SH3GLB1
SH3GLB2
SHISA6
SNW1
SPTA1
TEX11
TFIP11
TLE5
TNFAIP1
TRIB3
TRIM54
TRIM62
ZFP90
ZMAT1
ZNF420
ZNF558
ZNF620
ZNF655
ZNF792
Entrez ID
79027
56915
HPRD ID
11673
16222
Ensembl ID
ENSG00000197343
ENSG00000077348
Uniprot IDs
Q68DU4
Q8N720
Q9NQT4
PDB IDs
2NN6
6D6Q
6D6R
6H25
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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