SMURF2 and LATS1

  • Data Source:
  • BioGRID (unspecified method)

SMURF2

LATS1

Description SMAD specific E3 ubiquitin protein ligase 2 large tumor suppressor kinase 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cardiac troponin-I levels ( 31014085)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Joint mobility (Beighton score) ( 27182965)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Periodontitis (Mean PAL) ( 24024966)
  • Brain morphology (MOSTest) ( 32665545)
  • Nicotine dependence and major depression (severity of comorbidity) ( 30287806)
  • Subcortical volume (MOSTest) ( 32665545)
  • Testicular germ cell tumor ( 28604728)
Interacting Genes 91 interacting genes: ABRAXAS2 ACBD3 ACOX3 AIMP2 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CNKSR2 CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FKBP4 FLNB FUBP1 GNG2 HDGFL3 ING2 IRF3 IRF8 ITGB1BP1 KLF5 LAPTM5 LATS1 LMNA MAVS NEK6 NKIRAS1 NRAS PDE4B PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RTN4IP1 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNCA SNRNP70 SOCS6 SPART SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TOP2A TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 USP15 XPO1 YY1 ZBTB44 48 interacting genes: ALPP APP ARPC3 AURKB CAV1 CBY2 CDC26 CDK1 CEP76 EIF4EBP1 FOXL2 FSD2 GOLGA2 KRT31 LDOC1 LIMK1 LRRK2 MAGI3 MOAP1 MOB3A MOB3B MOB3C MOB4 NEDD4 NF2 NUAK1 NUAK2 OSTF1 PABPN1 PPM1F PPP1R11 PPP6R3 PTEN RAC1 SMURF1 SMURF2 SSX2IP STK3 STK4 TAZ TFIP11 TRAF1 UBE2I UBQLN2 WWOX WWP1 WWTR1 ZYX
Entrez ID 64750 9113
HPRD ID 06901 09147
Ensembl ID ENSG00000108854 ENSG00000131023
Uniprot IDs Q96DE7 Q9HAU4 O95835
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 6FX4 4ZRK 5B5W 5BRK
Enriched GO Terms of Interacting Partners?
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