SHB and SLC39A1

Data Source:
HPRD (two hybrid)

		SHB	SLC39A1
Description		SH2 domain containing adaptor protein B	solute carrier family 39 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Cytoplasmic Ribonucleoprotein Granule	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Phosphotyrosine Residue Binding Protein Binding	Signaling Receptor Binding Zinc Ion Transmembrane Transporter Activity Protein Binding Inorganic Cation Transmembrane Transporter Activity
	Biological Process	Angiogenesis Apoptotic Process Signal Transduction Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway	In Utero Embryonic Development Cation Transport Embryonic Cranial Skeleton Morphogenesis Limb Development Zinc Ion Transmembrane Transport
Pathways		VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway	Zinc influx into cells by the SLC39 gene family
Drugs
Diseases
GWAS		Brain structure ( 20171287) Chronotype ( 30696823) Loneliness (linear analysis) ( 27629369) Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878) Type 2 diabetes (age of onset) ( 28060188)	Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Lentiform nucleus volume ( 22903471) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		27 interacting genes: ABL1 AR CRK EGFR EPS8 ERBB2 ERBB3 ERBB4 GRAP2 GRB2 IL2RB IL2RG JAK1 JAK3 KDR KIT LAMTOR5 LAT LCP2 MET PDGFRA PIK3R1 PLCG1 SLC39A1 SRC VAV1 ZAP70	16 interacting genes: CERS2 COMT CXCL16 CXCL9 CYB561 HTR2C HTR4 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2 TRARG1 YIPF6
Entrez ID		6461	27173
HPRD ID		02635	11984
Ensembl ID		ENSG00000107338	ENSG00000143570
Uniprot IDs		Q15464	A0A0A0MTL8 Q9NY26
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?