RHEB and PPP1R3C

Data Source:
BioGRID (affinity chromatography technology)

		RHEB	PPP1R3C
Description		Ras homolog, mTORC1 binding	protein phosphatase 1 regulatory subunit 3C
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Spliceosomal Complex Lysosomal Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Postsynaptic Density Membrane Extracellular Exosome	Protein Phosphatase Type 1 Complex Cytosol
	Molecular Function	Magnesium Ion Binding GTPase Activity Protein Binding GTP Binding GDP Binding Protein Kinase Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Protein Phosphatase 1 Binding Protein Phosphatase Binding Glycogen Binding
	Biological Process	Cell Cycle Arrest Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Positive Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Cold-induced Thermogenesis Regulation Of Type B Pancreatic Cell Development	Glycogen Metabolic Process Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process Protein Dephosphorylation
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of PTEN gene transcription Amino acids regulate mTORC1	Glycogen synthesis Myoclonic epilepsy of Lafora
Drugs		Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: A2M APOE APPBP2 ARIH2 ATM ATR BNIP3 BNIP3L BRAF CREB3 ECSIT FKBP8 HTT MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RNF152 RPS6KB1 RPTOR TRIM55 TRIM63 TSC1 TSC2 USP4	9 interacting genes: APP EPM2A LONRF1 LXN NHLRC1 PPP1CA PPP1CB PPP1CC SGTA
Entrez ID		6009	5507
HPRD ID		03188	04298
Ensembl ID		ENSG00000106615	ENSG00000119938
Uniprot IDs		A0A090N900 Q15382	Q9UQK1
PDB IDs		1XTQ 1XTR 1XTS 3SEA 3T5G 5YXH 6BCU 6BSX 6BT0 7BTA 7BTC 7BTD
Enriched GO Terms of Interacting Partners?
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