ARHGAP21 and EEF1D

Data Source:
BioGRID (pull down)

		ARHGAP21	EEF1D
Description		Rho GTPase activating protein 21	eukaryotic translation elongation factor 1 delta
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GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol Plasma Membrane Actin Cytoskeleton Cell Junction Cytoplasmic Vesicle Membrane	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	GTPase Activator Activity Protein Binding	DNA Binding Translation Elongation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Factor Activity, RNA Binding Cadherin Binding
	Biological Process	Golgi Organization Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Golgi Localization Establishment Of Golgi Localization Maintenance Of Golgi Location Organelle Transport Along Microtubule	Translational Elongation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Catalytic Activity Cellular Response To Ionizing Radiation
Pathways		Rho GTPase cycle	Eukaryotic Translation Elongation
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Birth weight ( 31043758) Diisocyanate-induced asthma ( 25918132) Immature fraction of reticulocytes ( 32888494) Lobe attachment (rater scored) ( 29198719) Lobe attachment (rater-scored or self-reported) ( 29198719) Optic disc area ( 31798171) Optic disc size ( 31809533) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Triglyceride levels x loop diuretics use interaction ( 31806883)	Schizophrenia ( 31268507)
Interacting Genes		7 interacting genes: ARF1 EEF1D PTK2B RHOA SP1 TULP3 ZNF177	41 interacting genes: ABTB1 ALX1 APP ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CDK9 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS1 ERP27 FKBP6 FOS FRA10AC1 GARS1 HEXD HSF1 KARS1 KTN1 MAP1B NR2F1 POT1 PRKCA RELA RNF40 RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 UBE2A VARS1
Entrez ID		57584	1936
HPRD ID		06445	00560
Ensembl ID		ENSG00000107863	ENSG00000104529
Uniprot IDs		Q5T5U3	B2RAR6 D3DWK1 P29692
PDB IDs		2DHJ 2J59 2YUY	2MVM 2MVN 2N51 5JPO
Enriched GO Terms of Interacting Partners?
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