PGLYRP4 and TRPC4AP

Data Source:
BioGRID (proximity labelling technology)

		PGLYRP4	TRPC4AP
Description		peptidoglycan recognition protein 4	transient receptor potential cation channel subfamily C member 4 associated protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Membrane Protein-containing Complex	Plasma Membrane Cul4A-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Zinc Ion Binding N-acetylmuramoyl-L-alanine Amidase Activity Peptidoglycan Immune Receptor Activity Peptidoglycan Binding Protein Heterodimerization Activity	Protein Binding Phosphatase Binding
	Biological Process	Peptidoglycan Catabolic Process Detection Of Bacterium Killing Of Cells Of Other Organism Innate Immune Response Defense Response To Gram-positive Bacterium Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Hair Follicle Maturation Calcium Ion Transmembrane Transport
Pathways		Antimicrobial peptides	TRP channels
Drugs
Diseases
GWAS		Asthma ( 31619474)	Blood protein levels ( 28240269) Fish- and plant-related diet ( 32066663) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Prothrombin time ( 22703881) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes			10 interacting genes: CHMP4C CHUK IKBKB IKBKG MTDH RIPK1 TAB1 TNFRSF1A TRADD TRAF2
Entrez ID		57115	26133
HPRD ID		16298	09238
Ensembl ID		ENSG00000163218	ENSG00000100991
Uniprot IDs		Q96LB8	B4DW48 Q8TEL6
PDB IDs		2EAV 2EAX
Enriched GO Terms of Interacting Partners?
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