INTS8 and TMEM67

Data Source:
BioGRID (affinity chromatography technology)

		INTS8	TMEM67
Description		integrator complex subunit 8	transmembrane protein 67
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Integrator Complex	Endoplasmic Reticulum Membrane Centrosome Integral Component Of Membrane Cytoplasmic Vesicle Membrane Ciliary Transition Zone MKS Complex Ciliary Membrane
	Molecular Function	Protein Binding	Protein Binding Filamin Binding Unfolded Protein Binding
	Biological Process	SnRNA Processing SnRNA 3'-end Processing SnRNA Transcription By RNA Polymerase II	Negative Regulation Of Centrosome Duplication Ubiquitin-dependent ERAD Pathway Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Anchoring of the basal body to the plasma membrane
Drugs
Diseases			Joubert syndrome COACH syndrome Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2) Meckel syndrome (MKS); Meckel-Gruber syndrome
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Molybdenum levels ( 26025379) Multiple sclerosis ( 31604244) Type 2 diabetes ( 25102180)
Interacting Genes		1 interacting genes: CTDP1	2 interacting genes: MKS1 UBQLN1
Entrez ID		55656	91147
HPRD ID		08626	11324
Ensembl ID		ENSG00000164941	ENSG00000164953
Uniprot IDs		Q75QN2	Q5HYA8
PDB IDs
Enriched GO Terms of Interacting Partners?
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