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NOTCH3 and CPNE6
Data Source:
BioGRID
(pull down)
NOTCH3
CPNE6
Description
notch receptor 3
copine 6
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Extracellular Region
Nucleoplasm
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Cell Surface
Actin Cytoskeleton
Integral Component Of Membrane
Receptor Complex
Endosome
Plasma Membrane
Membrane
Axon
Dendrite
Perikaryon
Synapse
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Molecular Function
Calcium Ion Binding
Protein Binding
Signaling Receptor Activity
Identical Protein Binding
Cadherin Binding
Phosphatidylserine Binding
Transporter Activity
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Biological Process
Transcription Initiation From RNA Polymerase II Promoter
Notch Signaling Pathway
Positive Regulation Of Transcription Of Notch Receptor Target
Axon Guidance
Negative Regulation Of Notch Signaling Pathway
Regulation Of Developmental Process
Lipid Metabolic Process
Chemical Synaptic Transmission
Nervous System Development
Vesicle-mediated Transport
Cell Differentiation
Glycerophospholipid Biosynthetic Process
Cellular Response To Calcium Ion
Positive Regulation Of Dendrite Extension
Pathways
Pre-NOTCH Processing in the Endoplasmic Reticulum
Pre-NOTCH Transcription and Translation
Pre-NOTCH Processing in Golgi
Pre-NOTCH Processing in Golgi
Notch-HLH transcription pathway
Defective LFNG causes SCDO3
NOTCH3 Activation and Transmission of Signal to the Nucleus
NOTCH3 Activation and Transmission of Signal to the Nucleus
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
Noncanonical activation of NOTCH3
Glycerophospholipid biosynthesis
Drugs
Diseases
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)
GWAS
Pulse pressure (
27841878
30578418
)
Toxoplasma gondii sag1 antibody levels (
33204752
)
Triglyceride levels (
32203549
)
Interacting Genes
48 interacting genes:
ANKRD28
BAG2
BTF3L4
C1QL1
C8orf76
CBFA2T2
CHUK
CNTD1
CPNE6
CRIP2
CSNK2B
DLL1
EGFL7
FBLN1
GGT6
JAG1
JAG2
KAT2B
LINC00839
MAML1
MAML2
MAML3
MPPED2
MTDH
MYC
NEDD9
PPIA
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSEN1
PSEN2
RBPJ
RET
RMI2
SCGB3A1
SLC39A1
SNW1
SNX19
SORBS3
SPTLC2
TMEM108
TNNT2
TPT1
WDR25
XKR8
14 interacting genes:
AGR2
AK5
ANXA7
CDKN1A
GRB7
LAMTOR3
MAPK11
MEOX2
NOTCH3
OS9
PIN1
SMN1
TK1
TTR
Entrez ID
4854
9362
HPRD ID
02607
05748
Ensembl ID
ENSG00000074181
ENSG00000100884
Uniprot IDs
Q9UM47
B3KWK1
O95741
PDB IDs
4ZLP
5CZV
5CZX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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