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MIR205 and TRIM25
Data Source:
BioGRID
(unspecified method)
MIR205
TRIM25
Description
microRNA 205
tripartite motif containing 25
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Cytosol
Cytoplasmic Stress Granule
Nuclear Body
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Transcription Coactivator Activity
RNA Binding
Protein Binding
Ligase Activity
RIG-I Binding
Cadherin Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Receptor-mediated Endocytosis
Negative Regulation Of Inflammatory Response
Negative Regulation Of Fibroblast Growth Factor Production
Regulation Of Aorta Morphogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Positive Regulation Of Metalloendopeptidase Activity
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Viral Process
Translesion Synthesis
Ubiquitin-dependent ERAD Pathway
Negative Regulation Of Type I Interferon Production
Regulation Of Protein Localization
Response To Vitamin D
RIG-I Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Estrogen
Innate Immune Response
Positive Regulation Of Transcription, DNA-templated
Regulation Of Viral Entry Into Host Cell
Negative Regulation Of Viral Entry Into Host Cell
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Interferon-gamma-mediated Signaling Pathway
Regulation Of Viral Release From Host Cell
Negative Regulation Of Viral Release From Host Cell
Cellular Response To Leukemia Inhibitory Factor
Pathways
ISG15 antiviral mechanism
DDX58/IFIH1-mediated induction of interferon-alpha/beta
Termination of translesion DNA synthesis
Ovarian tumor domain proteases
Interferon gamma signaling
TRAF3-dependent IRF activation pathway
TRAF6 mediated IRF7 activation
TRAF6 mediated NF-kB activation
TRAF6 mediated NF-kB activation
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Negative regulators of DDX58/IFIH1 signaling
Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS
Height (
18391951
)
Lean body mass (
28552196
)
Interacting Genes
92 interacting genes:
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CELF1
CELF2
CPSF1
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NOL6
NONO
NUDT21
NUFIP2
PDCD11
PGAM5
PLRG1
PTBP1
PTBP3
PTCD3
PUF60
PURA
QARS1
RARS1
RBFOX2
RBM14
RBM4
RBM45
RBMS1
RBMS2
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZC3H7B
ZNF346
57 interacting genes:
AMFR
APC
DDX58
ERCC2
ERG
ESR1
GATA1
GRIK2
MAP3K13
MEIS2
MIR1-1
MIR155
MIR16-2
MIR19B2
MIR205
MIR206
MIR21
MIR221
MIR25
MIR29A
MIR29B1
MIR34A
MIR363
MIR7-1
MIR92A1
MIR92A2
MIR98
MIRLET7A1
MIRLET7A3
MTA1
OTUB2
PAX2
PITX2
PLAAT4
RBCK1
RNF31
SFN
STK11
STK38
SUMO2
TFG
TRAF6
TRIM8
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2J2
UBE2L3
UBE2L6
UBE2N
UBE2V1
USP15
USP39
YWHAQ
ZNF24
Entrez ID
406988
7706
HPRD ID
02711
Ensembl ID
ENSG00000284485
ENSG00000121060
Uniprot IDs
Q14258
PDB IDs
4CFG
4LTB
5EYA
5FER
5NT1
5NT2
6FLM
6FLN
Enriched GO Terms of Interacting Partners
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