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KRTAP10-8 and IL2RG
Data Source:
BioGRID
(two hybrid)
KRTAP10-8
IL2RG
Description
keratin associated protein 10-8
interleukin 2 receptor subunit gamma
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Keratin Filament
Endosome
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Membrane
Receptor Complex
Molecular Function
Protein Binding
Identical Protein Binding
Cytokine Receptor Activity
Interleukin-2 Receptor Activity
Interleukin-4 Receptor Activity
Interleukin-7 Receptor Activity
Protein Binding
Cytokine Binding
Interleukin-2 Binding
Interleukin-15 Receptor Activity
Biological Process
Keratinization
MAPK Cascade
Immune Response
Signal Transduction
Viral Process
Cytokine-mediated Signaling Pathway
Interleukin-15-mediated Signaling Pathway
Interleukin-4-mediated Signaling Pathway
Interleukin-2-mediated Signaling Pathway
Interleukin-7-mediated Signaling Pathway
Interleukin-9-mediated Signaling Pathway
Interleukin-21-mediated Signaling Pathway
Positive Regulation Of Phagocytosis
Pathways
Keratinization
Interleukin-7 signaling
Interleukin-7 signaling
RAF/MAP kinase cascade
Interleukin-4 and Interleukin-13 signaling
Interleukin-15 signaling
Interleukin-15 signaling
Interleukin-9 signaling
Interleukin-2 signaling
Interleukin-21 signaling
Interleukin receptor SHC signaling
Drugs
Denileukin diftitox
Aldesleukin
Resatorvid
Diseases
T-B+Severe combined immunodeficiencies (SCIDs), including the following eight diseases: X-linked SCID; Janus kinase-3 (Jak3) deficiency; IL-7 receptor alpha (IL7R alpha) deficiency; IL-2 receptor alpha (IL2R alpha) deficiency; CD45 deficiency; CD3 deficiency; Winged Helix Nude (WHN) deficiency; Immunodeficiency with thynoma
GWAS
Interacting Genes
388 interacting genes:
-
ACY3
ADAM12
ADAMTS1
ADAMTSL3
ADAMTSL4
AEBP2
AEN
AK3
ALDH3B1
ALPI
ALPP
AMMECR1
ANKS1A
AP1M1
APOL6
AQP1
AREG
ARID5A
ASPSCR1
ATG9A
ATP5F1D
AVPI1
AXIN2
BAHD1
BCL6B
BEX2
BMP7
BRME1
C10orf62
C11orf87
C17orf50
C19orf25
C22orf39
C2orf68
C3
CAMK1G
CARD10
CARHSP1
CATSPER1
CCDC26
CCNJL
CHIC2
CHRD
CHRNG
CLK4
CNNM3
COL8A1
COX17
CRCT1
CREB5
CRH
CRY2
CSF1
CTRC
CYP2S1
CYSRT1
DAAM2
DCX
DDX43
DDX55
DDX6
DERL2
DHRS1
DHX57
DMRT3
DOCK2
ECE1
EFEMP2
EIF4E2
ENKD1
EPDR1
FADS6
FAH
FAM110A
FAM161A
FAM221B
FAM27E3
FAM71C
FAM74A4
FAM76B
FAM90A1
FARS2
FBXO34
FBXW5
FEZF1
FOXB1
FRS3
FTHL17
FZD10
GEM
GFOD1
GLIDR
GLP1R
GLRX3
GLYAT
GNAI2
GNE
GOLGA8EP
GPANK1
GPHB5
GPRIN2
GRN
GUCD1
HAPLN2
HCK
HHEX
HOXA1
HOXB5
HOXB9
HOXC8
HPCAL1
HS6ST1
HSD3B7
HSPA12B
HSPD1
ICAM1
IGFBP6
IGSF8
IL10
IL16
IL2RG
INO80B
INTS5
IP6K3
ITGB2
ITGB4
ITGB5
JOSD1
JPH3
KLHL38
KLK8
KPRP
KRT20
KRT83
KRTAP1-1
KRTAP1-3
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-9
KRTAP11-1
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP15-1
KRTAP17-1
KRTAP19-7
KRTAP3-1
KRTAP3-2
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP4-7
KRTAP5-11
KRTAP5-2
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LAGE3
LASP1
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3B
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LELP1
LENG1
LINC00656
LMF2
LNX1
LRCH4
LRFN4
LUZP4
LYVE1
MACROH2A1
MAPKBP1
MATN3
MEIS2
MELTF
MEOX2
MLLT6
MOBP
MTA1
MUL1
MXI1
MYPOP
NAB2
NAXD
NBPF19
NECTIN2
NECTIN3
NEK6
NKD1
NOTCH2NLA
NPDC1
NR1D2
NR4A3
NTN4
NUFIP2
OLIG3
OPCML
OTX1
P2RX7
P2RY6
PAX5
PCED1A
PCSK5
PDE9A
PDIA4
PGAP6
PGLS
PHLDA1
PIGS
PIN1
PKD2
PLSCR4
POM121L8P
POU1F1
POU4F2
PRKAB2
PRPF31
PRR13
PRR19
PTGER3
PTK7
PTPMT1
PTPRH
PVR
QPRT
R3HDM2
RAB19
RAB3A
RALGDS
RANBP3
RASD1
RECK
RGL2
RHBDL1
RHNO1
RNF38
RNF8
RPS19BP1
RPS28
RTN4RL1
SCARF1
SCNM1
SEMA3B
SH3GLB2
SHFL
SLC13A5
SLC22A23
SLC23A1
SLC25A10
SLC25A31
SLC25A42
SLC6A20
SLIT1
SMARCE1
SMCP
SMG9
SMOC1
SPACA9
SPAG8
SPATA24
SPATA3
SPRY1
SPRY2
SSC4D
STK16
SUSD2
SUSD6
SUV39H1
TACSTD2
TAPBPL
TBC1D16
TBC1D23
TCAF1
TCEA2
TCEANC
TFAP2D
TGFB1
THAP10
THAP7
TIE1
TLE5
TMEM140
TMEM150A
TMIE
TNIP3
TNP2
TNPO3
TNS2
TRIM41
TRIM42
TRPV6
TSPAN4
TTC23
TXNDC5
TYMSOS
TYRO3
UBL5
UTP23
UXT
VASN
VENTX
VEZF1
VGLL3
VPS11
VWC2
VWC2L
WIF1
WNT11
WT1
WT1-AS
YIPF3
YY1
ZBTB24
ZBTB25
ZDHHC1
ZFYVE21
ZIC1
ZNF101
ZNF107
ZNF121
ZNF124
ZNF138
ZNF165
ZNF20
ZNF23
ZNF250
ZNF264
ZNF266
ZNF319
ZNF32
ZNF330
ZNF408
ZNF414
ZNF417
ZNF439
ZNF440
ZNF444
ZNF473
ZNF490
ZNF491
ZNF497
ZNF524
ZNF559
ZNF572
ZNF575
ZNF578
ZNF580
ZNF581
ZNF587
ZNF625
ZNF648
ZNF669
ZNF696
ZNF697
ZNF775
ZNF786
ZNF79
ZNF792
ZNF837
ZSCAN12
ZSCAN21
27 interacting genes:
AXL
CAPNS1
ERRFI1
ICAM1
IL15
IL15RA
IL2
IL2RB
IL4
IL4R
IL7
IL7R
IL9R
JAK1
JAK3
KRTAP10-3
KRTAP10-8
KRTAP5-7
NOTCH2NLA
PTPRJ
SHB
SHC1
STAT1
STAT5A
STK4
WWP1
WWP2
Entrez ID
386681
3561
HPRD ID
11194
02391
Ensembl ID
ENSG00000187766
ENSG00000147168
Uniprot IDs
P60410
P31785
PDB IDs
1ILL
1ILM
1ILN
1ITE
2B5I
2ERJ
3BPL
3QAZ
3QB7
4GS7
5M5E
6OEL
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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