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KRTAP6-3 and LGALS9
Data Source:
BioGRID
(two hybrid)
KRTAP6-3
LGALS9
Description
keratin associated protein 6-3
galectin 9
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Intermediate Filament
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Collagen-containing Extracellular Matrix
Molecular Function
Galactose Binding
Galactoside Binding
Enzyme Binding
Carbohydrate Binding
Disaccharide Binding
Biological Process
Keratinization
Natural Killer Cell Tolerance Induction
Chemotaxis
Inflammatory Response
Female Pregnancy
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Response To Lipopolysaccharide
Regulation Of Interleukin-4 Production
Regulation Of Interleukin-5 Production
Negative Regulation Of Chemokine Production
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Interferon-gamma Production
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-10 Production
Positive Regulation Of Interleukin-12 Production
Positive Regulation Of Interleukin-13 Production
Positive Regulation Of Interleukin-4 Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Involved In Immune Response
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
P38MAPK Cascade
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Mast Cell Degranulation
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Negative Regulation Of Activated T Cell Proliferation
Positive Regulation Of Viral Entry Into Host Cell
Positive Regulation Of NF-kappaB Transcription Factor Activity
Maternal Process Involved In Female Pregnancy
Positive Regulation Of Activated T Cell Autonomous Cell Death
ERK1 And ERK2 Cascade
Positive Regulation Of ERK1 And ERK2 Cascade
Response To Interleukin-1
Cellular Response To Interferon-gamma
Positive Regulation Of Transforming Growth Factor Beta Production
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Mature Conventional Dendritic Cell Differentiation
Cellular Response To Virus
Regulation Of P38MAPK Cascade
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Dendritic Cell Chemotaxis
Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Positive Regulation Of Dendritic Cell Apoptotic Process
Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Positive Regulation Of Dendritic Cell Differentiation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Pathways
Interleukin-2 family signaling
Drugs
(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
Crohn's disease (
23128233
)
Irritable mood (
29500382
)
Interacting Genes
159 interacting genes:
ADAMTSL4
AGXT
ARID5A
ARMC7
ATPAF2
AUTS2
BAG4
BEX2
BSCL2
C11orf87
CAMK2A
CAMK2B
CAMK2G
CARHSP1
CCDC120
CCDC24
CCER1
CELF5
CHRD
CLCNKA
CNNM3
COL8A1
CREB5
CRY2
CTSZ
CYSRT1
DALRD3
DHRS1
DMRT3
FADS6
FAM214B
FAM83A
FBXW5
FCHO1
FOXD2
FOXD4L1
GATA2
GATA3
GLYCTK
GNE
GPS2
HAPLN2
HHEX
HOXA1
HOXB5
HOXB9
HOXC8
HR
HYAL2
ILF2
INCA1
INPP5D
ITGB4
KANK2
KPRP
KRT20
KRTAP11-1
KRTAP12-2
KRTAP19-2
KRTAP19-5
KRTAP19-6
KRTAP19-7
KRTAP26-1
KRTAP4-4
KRTAP6-1
KRTAP6-2
LAGE3
LCE1B
LCE1C
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE3A
LCE3C
LCE3D
LCE3E
LCE5A
LGALS9
LNX1
MAGED1
MAPK1IP1L
MAPKBP1
MBD3L2
MED25
MEIS2
MEOX2
MGAT5B
NODAL
NOTO
NR4A3
OLIG3
OTX1
OXER1
P4HB
PATZ1
PCDHB14
PGAP6
PHETA1
PHLDA1
PIGS
PITX1
PLSCR4
POU4F2
POU4F3
PPP1R32
PPP1R37
PRMT8
PROP1
PRPF31
PRR13
PRR3
PRR35
PSMA1
PVR
RAB3IL1
RAD54L2
RASD1
RHBDL1
RUNX1T1
SAMD7
SEMA4C
SH3KBP1
SLC15A2
SLC22A5
SMARCC1
SMARCE1
SMCP
SNRPB
SNRPC
SNX18
STK16
STRA6
TAOK2
TBX2
TBX6
TCAF1
TCF7L2
TEKT4
TENT2
TEX45
TFAP2D
TLE5
TLX3
TNIP1
TNS2
TSPYL6
TYK2
VASN
VENTX
VSTM4
WDR25
ZBTB32
ZIC1
ZNF414
ZNF497
ZNF575
ZNF79
5 interacting genes:
DAZAP2
KRTAP6-3
P4HB
PDIA3
PDIA6
Entrez ID
337968
3965
HPRD ID
11220
03528
Ensembl ID
ENSG00000212938
ENSG00000168961
Uniprot IDs
A0A024QZ02
A0A024QZ55
O00182
PDB IDs
2EAK
2EAL
2YY1
2ZHK
2ZHL
2ZHM
2ZHN
3LSD
3LSE
3NV1
3NV2
3NV3
3NV4
3WLU
3WV6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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