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ECT2 and POMP
Data Source:
BioGRID
(two hybrid)
ECT2
POMP
Description
epithelial cell transforming 2
proteasome maturation protein
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cell-cell Junction
Bicellular Tight Junction
Cell Cortex
Nuclear Body
Midbody
Cleavage Furrow
Mitotic Spindle
Centralspindlin Complex
Nucleus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Nuclear Speck
Organelle Membrane
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
GTPase Activator Activity
Protein Binding
Small GTPase Binding
Protein Homodimerization Activity
Protein Binding
Biological Process
Mitotic Cytokinesis
Cell Morphogenesis
G Protein-coupled Receptor Signaling Pathway
Nervous System Development
Protein Transport
Cell Differentiation
Activation Of Protein Kinase Activity
Positive Regulation Of Cytokinesis
Intracellular Signal Transduction
Positive Regulation Of Protein Import Into Nucleus
Positive Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of GTPase Activity
Positive Regulation Of Neuron Differentiation
Regulation Of Protein Kinase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Protein Homooligomerization
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Cellular Response To Hydrogen Peroxide
Bicellular Tight Junction Assembly
Cellular Response To Calcium Ion
Cellular Response To Ionizing Radiation
Activation Of GTPase Activity
Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly
Proteasome Assembly
Pathways
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events
Drugs
Diseases
Keratosis linearis with ichthyosis congenita and sclerosing keratoderma; KLICK syndrome
GWAS
Obesity-related traits (
23251661
)
Red cell distribution width (
32888494
)
Breast cancer (menopausal hormone therapy interaction) (
24080446
)
Hematocrit (
32888494
27863252
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Interacting Genes
38 interacting genes:
ABR
C2orf42
CCDC91
CD19
CDK1
CHST10
CSTB
EIF4A2
EIF5B
ELOC
ERAL1
F2RL2
FANCM
GGN
ILVBL
KLHL20
LAMTOR5
MBD1
MT-CO2
MT2A
NOMO1
NPC2
OOSP2
OTUB1
PARD6A
PCOLCE
PLK1
POMP
PSMA6
RACGAP1
RHOG
RPS20
SNRNP200
SPATA22
SRPK2
THAP11
UBB
VDAC2
25 interacting genes:
ARMT1
ATXN1
CAPN3
ECT2
FAM107A
GPD1
GRB2
KCNA10
KIF1B
KLHL41
MPPED2
PSMA1
PSMA3
PSMB1
PSMB10
PSMB5
PSMB6
PSMB7
PSMB8
PSMB9
PYGM
RBM5
SSR4
TTN
VCL
Entrez ID
1894
51371
HPRD ID
11860
12613
Ensembl ID
ENSG00000114346
ENSG00000132963
Uniprot IDs
Q9H8V3
Q9Y244
PDB IDs
3L46
4N40
6L30
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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