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MOB3C and LATS2
Data Source:
BioGRID
(pull down)
MOB3C
LATS2
Description
MOB kinase activator 3C
large tumor suppressor kinase 2
Image
No pdb structure
GO Annotations
Cellular Component
Spindle Pole
Nucleus
Cytosol
Centriolar Satellite
Molecular Function
Protein Binding
Metal Ion Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Protein Phosphorylation
Hormone-mediated Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Peptidyl-serine Phosphorylation
Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Organ Growth
Cell Division
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Localization To Nucleus
Pathways
Signaling by Hippo
Drugs
Diseases
GWAS
Chronic kidney disease (
30226566
)
Hypertension (
30226566
)
3-month functional outcome in ischaemic stroke (modified Rankin score) (
30796134
)
Refractive error (
32231278
)
Interacting Genes
18 interacting genes:
APP
CMTM3
FAM118A
FBXO7
IKZF4
KANK2
KRT40
LATS1
LATS2
NT5C2
PCYT1A
PICK1
PTPN21
SIAH1
TDO2
TFCP2
TNIP1
ZBTB10
67 interacting genes:
ABL1
AJUBA
AKT1
ARAF
ARNT
AURKA
AURKB
BECN1
BRAF
CBLC
CCND2
CCNE1
CD44
CDK2
CDK4
CDK6
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CHEK1
CHEK2
CTNNB1
DYRK1A
EPHA2
ERBB2
EZH2
FGFR4
FHL3
FZR1
GLIS1
GLIS2
GRAP2
GRM1
HGF
HIF1A
KAT2A
KDELR2
KIF23
MAP2K3
MAP2K5
MAPK14
MDM4
MET
MOB3A
MOB3B
MOB3C
MOB4
MYC
NF2
NFIC
PDGFRA
RAF1
RASSF1
RELA
SMAD2
SNAI1
STK11
STK3
SUZ12
TAZ
TEAD2
TP53
TSC1
WWTR1
YWHAG
YWHAZ
Entrez ID
148932
26524
HPRD ID
17584
07277
Ensembl ID
ENSG00000142961
ENSG00000150457
Uniprot IDs
Q70IA8
X6R3L3
A0A024RDM3
Q9NRM7
PDB IDs
4ZRI
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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