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CATSPER1 and FRS3
Data Source:
BioGRID
(two hybrid)
CATSPER1
FRS3
Description
cation channel sperm associated 1
fibroblast growth factor receptor substrate 3
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Motile Cilium
CatSper Complex
Plasma Membrane
Molecular Function
Calcium Activated Cation Channel Activity
Voltage-gated Calcium Channel Activity
Protein Binding
Fibroblast Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
Biological Process
Calcium Ion Transport
Multicellular Organism Development
Spermatogenesis
Cell Differentiation
Flagellated Sperm Motility
Response To Progesterone
Regulation Of Ion Transmembrane Transport
Sperm-egg Recognition
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Calcium Ion Transmembrane Transport
MAPK Cascade
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Pathways
Sperm Motility And Taxes
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade
Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases
GWAS
Acne (severe) (
24927181
)
Bipolar disorder (
31043756
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Height (
31562340
)
Menarche (age at onset) (
25231870
)
Interacting Genes
116 interacting genes:
ABLIM3
ADAMTSL4
AGR2
AGR3
AJUBA
AKAP8L
APOA2
ARID5A
BEGAIN
C11orf1
C11orf16
C9orf24
CARD10
CDPF1
CHIC2
CHRD
CPSF7
CTBP2
CYSRT1
EFEMP2
EMD
EYA2
FHL5
FRS3
FST
GLI1
HNRNPH1
HOXA1
IKZF3
KHDRBS2
KPRP
KRT31
KRTAP1-1
KRTAP1-3
KRTAP1-5
KRTAP10-1
KRTAP10-10
KRTAP10-11
KRTAP10-3
KRTAP10-4
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP12-1
KRTAP12-2
KRTAP12-3
KRTAP17-1
KRTAP19-5
KRTAP19-6
KRTAP19-7
KRTAP2-3
KRTAP2-4
KRTAP3-2
KRTAP4-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-4
KRTAP4-7
KRTAP5-11
KRTAP5-3
KRTAP5-4
KRTAP5-6
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP9-2
KRTAP9-3
KRTAP9-4
KRTAP9-8
LASP1
LCE1D
LCE1E
LCE1F
LCE2C
LIMS1
LZTS2
MDFI
MTUS2
MYCL
NBPF19
NOTCH2NLA
PAK5
PDLIM7
PLA2G10
PLAGL2
PLSCR1
PLSCR3
PMF1-BGLAP
PPP1R32
PTPN21
RFX6
RGS19
RGS20
RIMBP3
RSPO2
SCRG1
SIVA1
SORBS3
SPRY2
SPRY3
SSC4D
TGFB1
TNS2
TRAF2
TRIM27
TRIM42
TRIM8
TRIP6
TSPAN4
VWC2
ZBTB42
ZIM2
ZNF688
ZNF774
ZNF837
111 interacting genes:
ADAMTSL4
ANAPC11
ANKRD55
ATP23
BLZF1
BMPR2
C11orf1
C11orf45
C19orf54
C22orf39
CATSPER1
CBY2
CCDC33
CCN3
CDPF1
COL8A1
COPS3
CREB5
CYSRT1
DCDC2B
DDX5
DMRT3
DPEP2NB
ECM1
ESM1
FGFR1
GATA1
GPRIN2
GRB14
GRB2
HOXA1
HOXD12
ID2
ID3
IKZF3
INCA1
ISY1-RAB43
KARS1
KATNBL1
KIAA0408
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT76
KRTAP1-1
KRTAP10-8
KRTAP11-1
KRTAP3-1
KRTAP3-2
KRTAP6-2
LINGO1
LRRC18
MAPK1
MATK
MBD3L1
MIIP
NADSYN1
NBPF19
NOTCH2NLA
NTRK1
NTRK2
NUMB
PCSK5
PDLIM7
PIH1D2
PLB1
PLLP
PLSCR1
POF1B
PPP1R32
PRDM6
PRKCI
PTPN11
RFX6
RIMBP3C
RND1
SCNM1
SH2B1
SLAIN1
SLC22A18AS
SOCS6
SPATA12
SPRY2
STH
STK16
TCF4
TCP10L
TGM7
TLE5
TNS1
TRAF4
TRIP6
TSC1
TSGA10IP
TSPAN4
UNKL
VASP
VGLL3
WDR83
WWOX
YPEL3
ZMIZ2
ZNF124
ZNF417
ZNF438
ZNF446
ZNF552
ZNF69
ZSCAN30
Entrez ID
117144
10817
HPRD ID
09396
06373
Ensembl ID
ENSG00000175294
ENSG00000137218
Uniprot IDs
Q8NEC5
A0A140VJJ7
O43559
PDB IDs
2KUP
2KUQ
2YS5
2YT2
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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