| ALG13 |
ALG13 UDP-N-acetylglucosaminyltransferase subunit |
- Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
- Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
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| ATN1 |
atrophin 1 |
- Regulation of PTEN gene transcription
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| CBFA2T2 |
CBFA2/RUNX1 partner transcriptional co-repressor 2 |
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| CCDC120 |
coiled-coil domain containing 120 |
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| ECM1 |
extracellular matrix protein 1 |
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| EFEMP1 |
EGF containing fibulin extracellular matrix protein 1 |
- Molecules associated with elastic fibres
- Molecules associated with elastic fibres
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| EFEMP2 |
EGF containing fibulin extracellular matrix protein 2 |
- Molecules associated with elastic fibres
- Molecules associated with elastic fibres
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| EHMT2 |
euchromatic histone lysine methyltransferase 2 |
- Senescence-Associated Secretory Phenotype (SASP)
- PKMTs methylate histone lysines
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- Regulation of TP53 Activity through Methylation
- RNA Polymerase I Transcription Initiation
- Transcriptional Regulation by VENTX
- Transcriptional Regulation by E2F6
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| FBXO42 |
F-box protein 42 |
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| H3C14 |
H3 clustered histone 14 |
- Interleukin-7 signaling
- Interleukin-7 signaling
- Pre-NOTCH Transcription and Translation
- Formation of the beta-catenin:TCF transactivating complex
- PRC2 methylates histones and DNA
- Condensation of Prophase Chromosomes
- Oxidative Stress Induced Senescence
- Senescence-Associated Secretory Phenotype (SASP)
- HDACs deacetylate histones
- PKMTs methylate histone lysines
- HDMs demethylate histones
- HATs acetylate histones
- HATs acetylate histones
- RMTs methylate histone arginines
- Chromatin modifying enzymes
- SIRT1 negatively regulates rRNA expression
- ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
- NoRC negatively regulates rRNA expression
- NoRC negatively regulates rRNA expression
- B-WICH complex positively regulates rRNA expression
- DNA methylation
- Transcriptional regulation by small RNAs
- Activation of anterior HOX genes in hindbrain development during early embryogenesis
- Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
- RNA Polymerase I Promoter Opening
- RNA Polymerase I Promoter Escape
- RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Estrogen-dependent gene expression
- Meiotic recombination
- HCMV Early Events
- HCMV Late Events
- Transcriptional regulation of granulopoiesis
- Defective pyroptosis
- Amyloid fiber formation
- Factors involved in megakaryocyte development and platelet production
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| HSPB7 |
heat shock protein family B (small) member 7 |
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| KAT6A |
lysine acetyltransferase 6A |
- HATs acetylate histones
- Regulation of TP53 Activity through Acetylation
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| KRTAP12-4 |
keratin associated protein 12-4 |
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| KRTAP4-12 |
keratin associated protein 4-12 |
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| KRTAP6-2 |
keratin associated protein 6-2 |
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| LNPK |
lunapark, ER junction formation factor |
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| LZTR1 |
leucine zipper like transcription regulator 1 |
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| MITF |
melanocyte inducing transcription factor |
- SUMOylation of transcription factors
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| NR2E1 |
nuclear receptor subfamily 2 group E member 1 |
- Nuclear Receptor transcription pathway
- Regulation of PTEN gene transcription
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| PAF1 |
PAF1 homolog, Paf1/RNA polymerase II complex component |
- Formation of RNA Pol II elongation complex
- RNA Polymerase II Pre-transcription Events
- RNA Polymerase II Transcription Elongation
- E3 ubiquitin ligases ubiquitinate target proteins
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| PLSCR1 |
phospholipid scramblase 1 |
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| PRRC2A |
proline rich coiled-coil 2A |
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| PRRC2B |
proline rich coiled-coil 2B |
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| PSMA3 |
proteasome 20S subunit alpha 3 |
- Activation of NF-kappaB in B cells
- Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
- ER-Phagosome pathway
- Cross-presentation of soluble exogenous antigens (endosomes)
- Autodegradation of Cdh1 by Cdh1:APC/C
- SCF-beta-TrCP mediated degradation of Emi1
- APC/C:Cdc20 mediated degradation of Securin
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A
- Vpu mediated degradation of CD4
- Vif-mediated degradation of APOBEC3G
- SCF(Skp2)-mediated degradation of p27/p21
- Degradation of beta-catenin by the destruction complex
- Downstream TCR signaling
- Regulation of activated PAK-2p34 by proteasome mediated degradation
- Separation of Sister Chromatids
- FCERI mediated NF-kB activation
- Autodegradation of the E3 ubiquitin ligase COP1
- Regulation of ornithine decarboxylase (ODC)
- ABC-family proteins mediated transport
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- Asymmetric localization of PCP proteins
- Degradation of AXIN
- Degradation of DVL
- Hedgehog ligand biogenesis
- Hh mutants are degraded by ERAD
- Dectin-1 mediated noncanonical NF-kB signaling
- CLEC7A (Dectin-1) signaling
- Degradation of GLI1 by the proteasome
- Degradation of GLI2 by the proteasome
- GLI3 is processed to GLI3R by the proteasome
- Hedgehog 'on' state
- Regulation of RAS by GAPs
- TNFR2 non-canonical NF-kB pathway
- NIK-->noncanonical NF-kB signaling
- Defective CFTR causes cystic fibrosis
- MAPK6/MAPK4 signaling
- UCH proteinases
- Ub-specific processing proteases
- CDT1 association with the CDC6:ORC:origin complex
- Orc1 removal from chromatin
- CDK-mediated phosphorylation and removal of Cdc6
- G2/M Checkpoints
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
- Ubiquitin-dependent degradation of Cyclin D
- The role of GTSE1 in G2/M progression after G2 checkpoint
- FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
- ROS sensing by NFE2L2
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- Regulation of RUNX2 expression and activity
- Regulation of RUNX2 expression and activity
- Regulation of RUNX3 expression and activity
- Regulation of PTEN stability and activity
- Neddylation
- Regulation of expression of SLITs and ROBOs
- Interleukin-1 signaling
- Negative regulation of NOTCH4 signaling
- Antigen processing: Ubiquitination & Proteasome degradation
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- (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE
- Phenethyl Isothiocyanate
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| RBFOX2 |
RNA binding fox-1 homolog 2 |
- FGFR2 alternative splicing
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| SNRPC |
small nuclear ribonucleoprotein polypeptide C |
- mRNA Splicing - Major Pathway
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| TRIM22 |
tripartite motif containing 22 |
- Interferon gamma signaling
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| TRIP6 |
thyroid hormone receptor interactor 6 |
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| ZBTB17 |
zinc finger and BTB domain containing 17 |
- XBP1(S) activates chaperone genes
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| ZMYND8 |
zinc finger MYND-type containing 8 |
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| ZNF239 |
zinc finger protein 239 |
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