| CCL4 |
C-C motif chemokine ligand 4 |
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
- Interleukin-10 signaling
|
|
|
| CRK |
CRK proto-oncogene, adaptor protein |
- ARMS-mediated activation
- ARMS-mediated activation
- Downstream signal transduction
- Regulation of actin dynamics for phagocytic cup formation
- p130Cas linkage to MAPK signaling for integrins
- VEGFA-VEGFR2 Pathway
- PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
- MET activates RAP1 and RAC1
- MET receptor recycling
- Regulation of signaling by CBL
- FCGR3A-mediated phagocytosis
|
|
|
| CYTH2 |
cytohesin 2 |
|
- Inositol 1,3,4,5-Tetrakisphosphate
- Formic acid
- 1D-myo-inositol 1,4,5-trisphosphate
- S,S-(2-Hydroxyethyl)Thiocysteine
- Brefeldin A
|
|
| FAM221A |
family with sequence similarity 221 member A |
|
|
|
| FATE1 |
fetal and adult testis expressed 1 |
|
|
|
| NEDD4 |
NEDD4 E3 ubiquitin protein ligase |
- ISG15 antiviral mechanism
- Downregulation of ERBB4 signaling
- Regulation of PTEN localization
- Regulation of PTEN stability and activity
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
| NEDD4L |
NEDD4 like E3 ubiquitin protein ligase |
- Budding and maturation of HIV virion
- Downregulation of TGF-beta receptor signaling
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Stimuli-sensing channels
- Antigen processing: Ubiquitination & Proteasome degradation
|
|
|
| NKG7 |
natural killer cell granule protein 7 |
|
|
|
| PPP2R1A |
protein phosphatase 2 scaffold subunit Aalpha |
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Spry regulation of FGF signaling
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- Integration of energy metabolism
- PP2A-mediated dephosphorylation of key metabolic factors
- DARPP-32 events
- Degradation of beta-catenin by the destruction complex
- Beta-catenin phosphorylation cascade
- ERK/MAPK targets
- ERKs are inactivated
- MASTL Facilitates Mitotic Progression
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Regulation of PLK1 Activity at G2/M Transition
- Initiation of Nuclear Envelope (NE) Reformation
- Loss of Nlp from mitotic centrosomes
- Recruitment of mitotic centrosome proteins and complexes
- Loss of proteins required for interphase microtubule organization from the centrosome
- Recruitment of NuMA to mitotic centrosomes
- CTLA4 inhibitory signaling
- Platelet sensitization by LDL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Signaling by GSK3beta mutants
- S33 mutants of beta-catenin aren't phosphorylated
- S37 mutants of beta-catenin aren't phosphorylated
- S45 mutants of beta-catenin aren't phosphorylated
- T41 mutants of beta-catenin aren't phosphorylated
- APC truncation mutants have impaired AXIN binding
- AXIN missense mutants destabilize the destruction complex
- Truncations of AMER1 destabilize the destruction complex
- Anchoring of the basal body to the plasma membrane
- RHO GTPases Activate Formins
- RAF activation
- Negative regulation of MAPK pathway
- Regulation of TP53 Degradation
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- Mitotic Prometaphase
- Cyclin D associated events in G1
- Cyclin A/B1/B2 associated events during G2/M transition
- AURKA Activation by TPX2
- Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
- EML4 and NUDC in mitotic spindle formation
- Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
|
- 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid
- (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid
|
|
| RTN4RL1 |
reticulon 4 receptor like 1 |
- Post-translational modification: synthesis of GPI-anchored proteins
|
|
|
| SGTA |
small glutamine rich tetratricopeptide repeat co-chaperone alpha |
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
|
|
|
| SNX15 |
sorting nexin 15 |
|
|
|
| WWTR1 |
WW domain containing transcription regulator 1 |
- Signaling by Hippo
- YAP1- and WWTR1 (TAZ)-stimulated gene expression
- YAP1- and WWTR1 (TAZ)-stimulated gene expression
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Physiological factors
- RUNX2 regulates osteoblast differentiation
- RUNX3 regulates YAP1-mediated transcription
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
|
|
|
| YAP1 |
Yes1 associated transcriptional regulator |
- Nuclear signaling by ERBB4
- Signaling by Hippo
- YAP1- and WWTR1 (TAZ)-stimulated gene expression
- RUNX1 regulates transcription of genes involved in differentiation of HSCs
- RUNX2 regulates osteoblast differentiation
- RUNX3 regulates YAP1-mediated transcription
- EGR2 and SOX10-mediated initiation of Schwann cell myelination
|
|
|