HiPPIP

Search Results for: DTNBP1

58 interactions involving DTNBP1 - dystrobrevin binding protein 1 found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
ABI3 ABI family member 3
AKAP6 A-kinase anchoring protein 6
ARFIP2 ADP ribosylation factor interacting protein 2
  • Retrograde transport at the Trans-Golgi-Network
BICRAL BICRA like chromatin remodeling complex associated protein
BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3
  • Golgi Associated Vesicle Biogenesis
BLOC1S5 biogenesis of lysosomal organelles complex 1 subunit 5
BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6
  • Golgi Associated Vesicle Biogenesis
BRF1 BRF1 RNA polymerase III transcription initiation factor subunit
  • RNA Polymerase III Abortive And Retractive Initiation
  • RNA Polymerase III Transcription Initiation From Type 1 Promoter
  • RNA Polymerase III Transcription Initiation From Type 1 Promoter
  • RNA Polymerase III Transcription Initiation From Type 2 Promoter
  • RNA Polymerase III Transcription Initiation From Type 2 Promoter
CAP2 cyclase associated actin cytoskeleton regulatory protein 2
  • Role of ABL in ROBO-SLIT signaling
CCDC146 coiled-coil domain containing 146
CCDC153 coiled-coil domain containing 153
CCNA2 cyclin A2
  • Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
  • G0 and Early G1
  • Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
  • Telomere Extension By Telomerase
  • Cdc20:Phospho-APC/C mediated degradation of Cyclin A
  • Regulation of APC/C activators between G1/S and early anaphase
  • SCF(Skp2)-mediated degradation of p27/p21
  • Senescence-Associated Secretory Phenotype (SASP)
  • DNA Damage/Telomere Stress Induced Senescence
  • Ub-specific processing proteases
  • Processing of DNA double-strand break ends
  • TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
  • Regulation of TP53 Activity through Phosphorylation
  • Regulation of TP53 Degradation
  • G2 Phase
  • Orc1 removal from chromatin
  • CDK-mediated phosphorylation and removal of Cdc6
  • Cyclin A/B1/B2 associated events during G2/M transition
  • Cyclin A/B1/B2 associated events during G2/M transition
  • p53-Dependent G1 DNA Damage Response
  • Cyclin A:Cdk2-associated events at S phase entry
  • 4-(2,4-Dimethyl-Thiazol-5-Yl)-Pyrimidin-2-Ylamine
  • 6-O-Cyclohexylmethyl Guanine
  • [4-(2-Amino-4-Methyl-Thiazol-5-Yl)-Pyrimidin-2-Yl]-(3-Nitro-Phenyl)-Amine
  • 4-(2,4-Dimethyl-1,3-thiazol-5-yl)-N-[4-(trifluoromethyl)phenyl]-2-pyrimidinamine
  • 4-[(7-OXO-7H-THIAZOLO[5,4-E]INDOL-8-YLMETHYL)-AMINO]-N-PYRIDIN-2-YL-BENZENESULFONAMIDE
  • N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide
  • 2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE
  • O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE
  • (2S)-N-[(3E)-5-Cyclopropyl-3H-pyrazol-3-ylidene]-2-[4-(2-oxo-1-imidazolidinyl)phenyl]propanamide
  • N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine
  • 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE
  • 5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE
  • 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]-2-FURYL}-N-METHYLBENZENESULFONAMIDE
  • 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE
  • 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE
  • 4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZOIC ACID
  • N-[4-(2,4-DIMETHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-N',N'-DIMETHYL-BENZENE-1,4-DIAMINE
  • 4-{[5-(CYCLOHEXYLOXY)[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-7-YL]AMINO}BENZENESULFONAMIDE
  • 1-(3,5-DICHLOROPHENYL)-5-METHYL-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID
  • 4-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine
  • 4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine
  • HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM
  • 4-Methyl-5-[(2Z)-2-{[4-(4-morpholinyl)phenyl]imino}-2,5-dihydro-4-pyrimidinyl]-1,3-thiazol-2-amine
  • 6-CYCLOHEXYLMETHYLOXY-2-(4'-HYDROXYANILINO)PURINE
  • 4-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)--BENZAMIDE
  • 3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE
  • (2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol
  • 3-({2-[(4-{[6-(CYCLOHEXYLMETHOXY)-9H-PURIN-2-YL]AMINO}PHENYL)SULFONYL]ETHYL}AMINO)PROPAN-1-OL
  • 1-methyl-8-(phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid
  • (2R)-2-({9-(1-methylethyl)-6-[(4-pyridin-2-ylbenzyl)amino]-9H-purin-2-yl}amino)butan-1-ol
  • 1-[4-(AMINOSULFONYL)PHENYL]-1,6-DIHYDROPYRAZOLO[3,4-E]INDAZOLE-3-CARBOXAMIDE
  • 4-{[4-AMINO-6-(CYCLOHEXYLMETHOXY)-5-NITROSOPYRIMIDIN-2-YL]AMINO}BENZAMIDE
  • Variolin B
CCND3 cyclin D3
  • Transcriptional regulation of white adipocyte differentiation
  • MAPK6/MAPK4 signaling
  • Cyclin D associated events in G1
  • Regulation of RUNX1 Expression and Activity
  • Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)
CMYA5 cardiomyopathy associated 5
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
  • Chondroitin sulfate biosynthesis
DCTN1 dynactin subunit 1
  • MHC class II antigen presentation
  • HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
  • XBP1(S) activates chaperone genes
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • Signaling by ALK fusions and activated point mutants
DEK DEK proto-oncogene
  • B-WICH complex positively regulates rRNA expression
  • Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
  • Transcriptional regulation of granulopoiesis
  • Transcriptional regulation of granulopoiesis
DGCR6L DiGeorge syndrome critical region gene 6 like
DST dystonin
  • Type I hemidesmosome assembly
  • RHOU GTPase cycle
  • RHOV GTPase cycle
  • RND3 GTPase cycle
  • RND2 GTPase cycle
  • RND1 GTPase cycle
DTNA dystrobrevin alpha
DTNB dystrobrevin beta
ELOVL7 ELOVL fatty acid elongase 7
  • Synthesis of very long-chain fatty acyl-CoAs
HAUS1 HAUS augmin like complex subunit 1
  • Regulation of PLK1 Activity at G2/M Transition
  • Loss of Nlp from mitotic centrosomes
  • Recruitment of mitotic centrosome proteins and complexes
  • Loss of proteins required for interphase microtubule organization from the centrosome
  • Recruitment of NuMA to mitotic centrosomes
  • Anchoring of the basal body to the plasma membrane
  • AURKA Activation by TPX2
HDGFL1 HDGF like 1
IFT20 intraflagellar transport 20
  • Intraflagellar transport
  • Intraflagellar transport
IPO5 importin 5
  • vRNP Assembly
KALRN kalirin RhoGEF kinase
  • NRAGE signals death through JNK
  • EPHB-mediated forward signaling
  • G alpha (q) signalling events
  • G alpha (12/13) signalling events
  • MAPK6/MAPK4 signaling
  • RHOA GTPase cycle
  • RAC1 GTPase cycle
  • RHOG GTPase cycle
KANSL1 KAT8 regulatory NSL complex subunit 1
  • HATs acetylate histones
KIAA0408 KIAA0408
KIFC3 kinesin family member C3
KRT75 keratin 75
  • Keratinization
  • Formation of the cornified envelope
MACF1 microtubule actin crosslinking factor 1
NBEA neurobeachin
  • Neurotransmitter receptors and postsynaptic signal transmission
  • PKA activation
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Assembly and cell surface presentation of NMDA receptors
NDN necdin, MAGE family member
  • Interleukin-4 and Interleukin-13 signaling
NECAB2 N-terminal EF-hand calcium binding protein 2
NUF2 NUF2 component of NDC80 kinetochore complex
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
NUP153 nucleoporin 153
  • ISG15 antiviral mechanism
  • Transport of the SLBP independent Mature mRNA
  • Transport of the SLBP Dependant Mature mRNA
  • Transport of Mature mRNA Derived from an Intronless Transcript
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • Rev-mediated nuclear export of HIV RNA
  • Transport of Ribonucleoproteins into the Host Nucleus
  • NS1 Mediated Effects on Host Pathways
  • Viral Messenger RNA Synthesis
  • NEP/NS2 Interacts with the Cellular Export Machinery
  • Regulation of Glucokinase by Glucokinase Regulatory Protein
  • Nuclear import of Rev protein
  • Vpr-mediated nuclear import of PICs
  • snRNP Assembly
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of ubiquitinylation proteins
  • Nuclear Pore Complex (NPC) Disassembly
  • Regulation of HSF1-mediated heat shock response
  • SUMOylation of SUMOylation proteins
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA replication proteins
  • SUMOylation of DNA replication proteins
  • Transcriptional regulation by small RNAs
  • Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
  • tRNA processing in the nucleus
  • HCMV Early Events
  • HCMV Late Events
OIP5 Opa interacting protein 5
  • Deposition of new CENPA-containing nucleosomes at the centromere
P4HA3 prolyl 4-hydroxylase subunit alpha 3
  • Collagen biosynthesis and modifying enzymes
PSME3 proteasome activator subunit 3
  • Activation of NF-kappaB in B cells
  • Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
  • ER-Phagosome pathway
  • Cross-presentation of soluble exogenous antigens (endosomes)
  • Autodegradation of Cdh1 by Cdh1:APC/C
  • SCF-beta-TrCP mediated degradation of Emi1
  • APC/C:Cdc20 mediated degradation of Securin
  • APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
  • Cdc20:Phospho-APC/C mediated degradation of Cyclin A
  • Vpu mediated degradation of CD4
  • Vif-mediated degradation of APOBEC3G
  • SCF(Skp2)-mediated degradation of p27/p21
  • Degradation of beta-catenin by the destruction complex
  • Downstream TCR signaling
  • Regulation of activated PAK-2p34 by proteasome mediated degradation
  • Separation of Sister Chromatids
  • FCERI mediated NF-kB activation
  • Autodegradation of the E3 ubiquitin ligase COP1
  • Regulation of ornithine decarboxylase (ODC)
  • ABC-family proteins mediated transport
  • AUF1 (hnRNP D0) binds and destabilizes mRNA
  • Asymmetric localization of PCP proteins
  • Degradation of AXIN
  • Degradation of DVL
  • Hedgehog ligand biogenesis
  • Hh mutants are degraded by ERAD
  • Dectin-1 mediated noncanonical NF-kB signaling
  • CLEC7A (Dectin-1) signaling
  • Degradation of GLI1 by the proteasome
  • Degradation of GLI2 by the proteasome
  • GLI3 is processed to GLI3R by the proteasome
  • Hedgehog 'on' state
  • Regulation of RAS by GAPs
  • TNFR2 non-canonical NF-kB pathway
  • NIK-->noncanonical NF-kB signaling
  • Defective CFTR causes cystic fibrosis
  • MAPK6/MAPK4 signaling
  • UCH proteinases
  • Ub-specific processing proteases
  • CDT1 association with the CDC6:ORC:origin complex
  • Orc1 removal from chromatin
  • CDK-mediated phosphorylation and removal of Cdc6
  • G2/M Checkpoints
  • Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
  • Ubiquitin-dependent degradation of Cyclin D
  • The role of GTSE1 in G2/M progression after G2 checkpoint
  • FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
  • ROS sensing by NFE2L2
  • RUNX1 regulates transcription of genes involved in differentiation of HSCs
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX2 expression and activity
  • Regulation of RUNX3 expression and activity
  • Regulation of PTEN stability and activity
  • Neddylation
  • Regulation of expression of SLITs and ROBOs
  • Interleukin-1 signaling
  • Negative regulation of NOTCH4 signaling
  • Antigen processing: Ubiquitination & Proteasome degradation
RAB11A RAB11A, member RAS oncogene family
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Vasopressin regulates renal water homeostasis via Aquaporins
  • Anchoring of the basal body to the plasma membrane
  • VxPx cargo-targeting to cilium
  • TBC/RABGAPs
  • RAB geranylgeranylation
  • 5'-Guanosine-Diphosphate-Monothiophosphate
  • Guanosine-5'-Diphosphate
RBSN rabenosyn, RAB effector
  • Toll Like Receptor 9 (TLR9) Cascade
  • Factors involved in megakaryocyte development and platelet production
RNF144B ring finger protein 144B
  • Antigen processing: Ubiquitination & Proteasome degradation
SDCBP syndecan binding protein
  • Ephrin signaling
  • Neurofascin interactions
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • Neutrophil degranulation
SFR1 SWI5 dependent homologous recombination repair protein 1
SHFL shiftless antiviral inhibitor of ribosomal frameshifting
SNAPIN SNAP associated protein
  • Golgi Associated Vesicle Biogenesis
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
  • Inactivation of CDC42 and RAC1
  • CDC42 GTPase cycle
  • RAC1 GTPase cycle
SSC5D scavenger receptor cysteine rich family member with 5 domains
  • Scavenging by Class B Receptors
SYNE1 spectrin repeat containing nuclear envelope protein 1
  • Meiotic synapsis
TPMT thiopurine S-methyltransferase
  • Methylation
  • Defective TPMT causes TPMT deficiency
  • Olsalazine
TRAF3IP1 TRAF3 interacting protein 1
  • Intraflagellar transport
  • Intraflagellar transport
TRIM2 tripartite motif containing 2
  • Interferon gamma signaling
TRIM27 tripartite motif containing 27
  • SUMOylation of ubiquitinylation proteins
  • Regulation of PTEN stability and activity
  • Suppression of apoptosis
TRIM9 tripartite motif containing 9
  • Antigen processing: Ubiquitination & Proteasome degradation
VRK2 VRK serine/threonine kinase 2
  • RAC1 GTPase cycle
  • RAC2 GTPase cycle
  • RHOD GTPase cycle
  • RHOG GTPase cycle
  • RAC3 GTPase cycle
WASHC3 WASH complex subunit 3
ZNF490 zinc finger protein 490
  • Generic Transcription Pathway