ERI1

Description		exoribonuclease 1
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	3'-5'-exoribonuclease Activity Protein Binding 3'-5' Exonuclease Activity RRNA Binding Ribosome Binding Metal Ion Binding Histone Pre-mRNA Stem-loop Binding
	Biological Process	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Gene Silencing By RNA RRNA 3'-end Processing Histone MRNA Catabolic Process
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder (early vs late onset) ( 34016946) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Eosinophil percentage of white cells ( 32888494) Fish- and plant-related diet ( 32066663) General factor of neuroticism ( 30867560) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Medication use (diuretics) ( 31015401) Morning person ( 30696823) Neuroticism ( 29255261) Platelet distribution width ( 32888494 27863252) Processed meat consumption ( 32066663) Red cell distribution width ( 32888494) Refractive error ( 32231278) Schizophrenia ( 28991256) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		2 interacting genes: OGT SLBP
Entrez ID		90459
HPRD ID		11784
Ensembl ID		ENSG00000104626
Uniprot IDs		A0A024R355 Q8IV48
PDB IDs		1W0H 1ZBH 1ZBU 4L8R 4QOZ
Enriched GO Terms of Interacting Partners?
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