TRIM4

Description		tripartite motif containing 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Gene Expression Protein Ubiquitination Innate Immune Response
Pathways		DDX58/IFIH1-mediated induction of interferon-alpha/beta Ovarian tumor domain proteases TRAF3-dependent IRF activation pathway TRAF6 mediated IRF7 activation TRAF6 mediated NF-kB activation TRAF6 mediated NF-kB activation NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Negative regulators of DDX58/IFIH1 signaling Negative regulators of DDX58/IFIH1 signaling Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Dehydroepiandrosterone sulphate levels ( 21533175) Estrone levels ( 29325096) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Serum metabolite levels ( 23093944) Tacrolimus trough concentration in kidney transplant patients ( 29160300)
Interacting Genes		4 interacting genes: MDM2 SRPK2 TRIM41 TRPM8
Entrez ID		89122
HPRD ID		15556
Ensembl ID		ENSG00000146833
Uniprot IDs		Q9C037
PDB IDs
Enriched GO Terms of Interacting Partners?
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