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DPM2

Description dolichyl-phosphate mannosyltransferase subunit 2, regulatory
Image No pdb structure
GO Annotations Cellular Component
  • Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) Complex
  • Endoplasmic Reticulum Membrane
  • Integral Component Of Endoplasmic Reticulum Membrane
  • Dolichol-phosphate-mannose Synthase Complex
Molecular Function
  • Protein Binding
  • Enzyme Activator Activity
  • Enzyme Regulator Activity
Biological Process
  • GPI Anchor Biosynthetic Process
  • Dolichol Metabolic Process
  • Regulation Of Protein Stability
  • Protein O-linked Mannosylation
  • Regulation Of Catalytic Activity
Pathways
  • Synthesis of dolichyl-phosphate mannose
  • Synthesis of glycosylphosphatidylinositol (GPI)
  • Defective DPM1 causes DPM1-CDG (CDG-1e)
  • Defective DPM3 causes DPM3-CDG (CDG-1o)
  • Defective DPM2 causes DPM2-CDG (CDG-1u)
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Glaucoma (primary angle closure) ( 27064256)
Interacting Genes 7 interacting genes: DPM1 DPM3 HLA-DMB PIGA PIGC SLC22A2 VKORC1
Entrez ID 8818
HPRD ID 16028
Ensembl ID ENSG00000136908
Uniprot IDs O94777
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025