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PLPP1

Description phospholipid phosphatase 1
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Caveola
  • Membrane
  • Apical Plasma Membrane
  • Membrane Raft
  • Extracellular Exosome
Molecular Function
  • Diacylglycerol Diphosphate Phosphatase Activity
  • Protein Binding
  • Phosphatidate Phosphatase Activity
  • Sphingosine-1-phosphate Phosphatase Activity
  • Lipid Phosphatase Activity
  • Ceramide-1-phosphate Phosphatase Activity
Biological Process
  • Phospholipid Metabolic Process
  • Sphingosine Metabolic Process
  • Ceramide Metabolic Process
  • Signal Transduction
  • Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway
  • Negative Regulation Of Cell Population Proliferation
  • Regulation Of Lipid Metabolic Process
  • Sphingolipid Biosynthetic Process
  • Intracellular Steroid Hormone Receptor Signaling Pathway
  • Androgen Receptor Signaling Pathway
  • Phospholipid Dephosphorylation
Pathways
  • Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS
  • Cocaine dependence ( 31212010)
  • Heel bone mineral density ( 30598549 28869591)
Interacting Genes 5 interacting genes: CREB3 FAHD1 FXYD1 GPR42 SSMEM1
Entrez ID 8611
HPRD ID 06178
Ensembl ID ENSG00000067113
Uniprot IDs A0A024QZS3 A0A024QZU7 O14494
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025