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KMT5C

Description lysine methyltransferase 5C
Image
GO Annotations Cellular Component
  • Condensed Chromosome, Centromeric Region
  • Heterochromatin
  • Nucleus
  • Nucleoplasm
  • Pericentric Heterochromatin
Molecular Function
  • Chromatin Binding
  • Protein Binding
  • Histone-lysine N-methyltransferase Activity
  • Histone Binding
  • Histone Methyltransferase Activity (H4-K20 Specific)
  • Metal Ion Binding
  • S-adenosyl-L-methionine Binding
Biological Process
  • DNA Repair
  • Histone H4-K20 Dimethylation
  • Histone H4-K20 Trimethylation
  • Positive Regulation Of Isotype Switching
  • Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
  • PKMTs methylate histone lysines
Drugs
Diseases
GWAS
Interacting Genes 4 interacting genes: H4C1 RB1 RBL1 RBL2
Entrez ID 84787
HPRD ID 15454
Ensembl ID ENSG00000133247
Uniprot IDs A0A0D9SF94 Q86Y97
PDB IDs 3RQ4
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025