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FZD6

Description frizzled class receptor 6
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum Membrane
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Cell Surface
  • Integral Component Of Membrane
  • Apical Plasma Membrane
  • Apicolateral Plasma Membrane
  • Cytoplasmic Vesicle Membrane
Molecular Function
  • Amyloid-beta Binding
  • G Protein-coupled Receptor Activity
  • Protein Binding
  • Wnt-protein Binding
  • Ubiquitin Protein Ligase Binding
  • Wnt-activated Receptor Activity
Biological Process
  • Neural Tube Closure
  • Hair Follicle Development
  • G Protein-coupled Receptor Signaling Pathway
  • Platelet Activation
  • Cell Proliferation In Midbrain
  • Non-canonical Wnt Signaling Pathway
  • Embryonic Nail Plate Morphogenesis
  • Inner Ear Morphogenesis
  • Negative Regulation Of DNA-binding Transcription Factor Activity
  • Establishment Of Body Hair Planar Orientation
  • Canonical Wnt Signaling Pathway
  • Wnt Signaling Pathway, Planar Cell Polarity Pathway
  • Negative Regulation Of Canonical Wnt Signaling Pathway
  • Midbrain Morphogenesis
Pathways
  • Class B/2 (Secretin family receptors)
  • Ca2+ pathway
  • Ca2+ pathway
  • PCP/CE pathway
  • PCP/CE pathway
  • Regulation of FZD by ubiquitination
  • Signaling by RNF43 mutants
Drugs
Diseases
GWAS
  • Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes 2 interacting genes: SFRP1 WNT4
Entrez ID 8323
HPRD ID 04559
Ensembl ID ENSG00000164930
Uniprot IDs A0A024R9E9 B4DL33 B4E236 O60353
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025