CDC45

Description		cell division cycle 45
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome DNA Replication Preinitiation Complex Ciliary Basal Body
	Molecular Function	Chromatin Binding DNA Replication Origin Binding Single-stranded DNA Binding Protein Binding
	Biological Process	DNA Replication Checkpoint Signaling Double-strand Break Repair Via Break-induced Replication DNA Replication Initiation Mitotic DNA Replication Preinitiation Complex Assembly
Pathways		Activation of ATR in response to replication stress Unwinding of DNA Activation of the pre-replicative complex G1/S-Specific Transcription
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		25 interacting genes: CAMK1G CDK4 CDKN1A CDKN2A CEP55 CSK GINS4 LCK MAPK3 MCM10 MCM2 MCM3 MCM6 MCM7 ORC1 ORC2 ORC3 ORC5 ORC6 POLA1 RAB4B TOPBP1 TRAPPC3 UBC ZRANB1
Entrez ID		8318
HPRD ID		09145
Ensembl ID		ENSG00000093009
Uniprot IDs		O75419
PDB IDs		5DGO 6XTX 6XTY
Enriched GO Terms of Interacting Partners?
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