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PHC3

Description polyhomeotic homolog 3
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • PcG Protein Complex
  • PRC1 Complex
Molecular Function
  • DNA Binding
  • Chromatin Binding
  • Protein Binding
  • Zinc Ion Binding
  • Histone Binding
Biological Process
  • Negative Regulation Of Transcription, DNA-templated
Pathways
  • Oxidative Stress Induced Senescence
  • SUMOylation of DNA damage response and repair proteins
  • SUMOylation of transcription cofactors
  • SUMOylation of chromatin organization proteins
  • SUMOylation of RNA binding proteins
  • SUMOylation of DNA methylation proteins
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
  • Regulation of PTEN gene transcription
  • Regulation of PTEN gene transcription
  • Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS
  • Appendicular lean mass ( 33097823)
Interacting Genes 4 interacting genes: AGR2 H3-4 HYPK OGT
Entrez ID 80012
HPRD ID 10149
Ensembl ID ENSG00000173889
Uniprot IDs B4E2T1 E7EX82 Q8NDX5
PDB IDs 4PZN 4PZO
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025