VEGFC

Description		vascular endothelial growth factor C
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen
	Molecular Function	Vascular Endothelial Growth Factor Receptor Binding Protein Binding Growth Factor Activity Chemoattractant Activity Vascular Endothelial Growth Factor Receptor 3 Binding
	Biological Process	Response To Hypoxia Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Sprouting Angiogenesis Positive Regulation Of Neuroblast Proliferation Substrate-dependent Cell Migration Signal Transduction Positive Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Animal Organ Morphogenesis Morphogenesis Of Embryonic Epithelium Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Angiogenesis Negative Regulation Of Blood Pressure Positive Regulation Of Protein Kinase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Secretion Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Mast Cell Chemotaxis Positive Regulation Of Lymphangiogenesis Positive Regulation Of Mesenchymal Stem Cell Proliferation Cellular Response To Leukemia Inhibitory Factor
Pathways		Platelet degranulation VEGF ligand-receptor interactions VEGF binds to VEGFR leading to receptor dimerization
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Chin dimples ( 27182965) HIV-1 viral setpoint ( 22174851) Idiopathic dilated cardiomyopathy ( 29495422) Intraocular pressure ( 29785010 31959993) Mastocytosis (KIT D816V positive) ( 33421400) Serum albumin level ( 29403010) Serum total protein level ( 29403010) Thyroid stimulating hormone levels ( 32769997)
Interacting Genes		3 interacting genes: FLT4 KDR SGTB
Entrez ID		7424
HPRD ID		03317
Ensembl ID		ENSG00000150630
Uniprot IDs		P49767
PDB IDs		2X1W 2X1X 4BSK
Enriched GO Terms of Interacting Partners?
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