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UQCRFS1

Description ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Respiratory Chain Complex III
  • Mitochondrial Respiratory Chain Complex IV
Molecular Function
  • Protein Binding
  • Ubiquinol-cytochrome-c Reductase Activity
  • Oxidoreductase Activity
  • Metal Ion Binding
  • 2 Iron, 2 Sulfur Cluster Binding
Biological Process
  • Respiratory Electron Transport Chain
  • Mitochondrial Respiratory Chain Complex III Assembly
  • Proton Transmembrane Transport
Pathways
  • Respiratory electron transport
Drugs
  • 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol
  • 6-Hydroxy-5-undecyl-4,7-benzothiazoledione
  • Azoxystrobin
  • 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione
  • (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE
  • (S)-famoxadone
  • METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE
  • 2-Nonyl-4-quinolinol 1-oxide
  • Ubiquinone Q2
Diseases
GWAS
  • Disease progression in age-related macular degeneration ( 29346644)
  • Methadone dose in opioid dependence ( 28115739)
  • Stroke ( 32693751)
Interacting Genes 4 interacting genes: CYC1 HTR6 RELB SOX5
Entrez ID 7386
HPRD ID 01874
Ensembl ID ENSG00000169021
Uniprot IDs P47985
PDB IDs 5XTE 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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