TPMT

Description thiopurine S-methyltransferase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • DNA-incorporated thioguanine levels in 6-mercaptopurine-treated acute lymphoblastic leukaemia ( 30201983)
  • Erythrocyte methylated 6-mercaptopurine metabolite concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia ( 30201983)
  • Erythrocyte thioguanine concentration in 6-mercaptopurine-treated acute lymphoblastic leukaemia ( 30201983)
  • Thiopurine methyltransferase activity in acute lymphoblastic leukemia patients treated with mercaptopurines ( 27564568)
  • Thiopurine S-methyltransferase activity ( 27770449)
  • Thiopurine-induced myelosuppression in inflammatory bowel disease ( 30806694)
Interacting Genes 3 interacting genes: APP DTNBP1 FGFR1
Entrez ID 7172
HPRD ID 01760
Ensembl ID ENSG00000137364
Uniprot IDs A0A024QZW0 P51580
PDB IDs 2BZG 2H11
Enriched GO Terms of Interacting Partners?
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