SERPING1

Description		serpin family G member 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Platelet Alpha Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Negative Regulation Of Complement Activation, Lectin Pathway Complement Activation, Classical Pathway Aging Blood Coagulation Blood Circulation Negative Regulation Of Endopeptidase Activity Fibrinolysis Innate Immune Response
Pathways		Platelet degranulation Intrinsic Pathway of Fibrin Clot Formation Defective SERPING1 causes hereditary angioedema Regulation of Complement cascade
Drugs		PPL-100 Copper
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 29875488 28240269) Mean platelet volume ( 32888494) Neuroticism ( 29255261) Obesity-related traits ( 23251661) Platelet count ( 32888494) Schizophrenia ( 25056061 29483656)
Interacting Genes		16 interacting genes: BAG6 C1R C1S ELANE ENO1 F2 HSP90AA1 MASP1 MASP2 NR4A1 PLAT PLG SELE SELP SLC30A2 SRPK2
Entrez ID		710
HPRD ID		06033
Ensembl ID		ENSG00000149131
Uniprot IDs		E9KL26 P05155
PDB IDs		1M6Q 2OAY 5DU3 5DUQ
Enriched GO Terms of Interacting Partners?
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