SORD

Description		sorbitol dehydrogenase
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GO Annotations	Cellular Component	Extracellular Space Cytosol Membrane Motile Cilium Mitochondrial Membrane Extracellular Exosome
	Molecular Function	(R,R)-butanediol Dehydrogenase Activity L-iditol 2-dehydrogenase Activity Zinc Ion Binding Carbohydrate Binding Identical Protein Binding D-xylulose Reductase Activity Ribitol 2-dehydrogenase Activity NAD Binding
	Biological Process	Glucose Metabolic Process Sorbitol Catabolic Process Response To Osmotic Stress Response To Xenobiotic Stimulus Response To Hormone Flagellated Sperm Motility Response To Nutrient Levels Fructose Biosynthetic Process Response To Cadmium Ion Response To Copper Ion L-xylitol Catabolic Process L-xylitol Metabolic Process
Pathways		Fructose biosynthesis Formation of xylulose-5-phosphate
Drugs		NADH Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476)
Interacting Genes		3 interacting genes: KRT5 RELA SHBG
Entrez ID		6652
HPRD ID		01679
Ensembl ID		ENSG00000140263
Uniprot IDs		Q00796
PDB IDs		1PL6 1PL7 1PL8
Enriched GO Terms of Interacting Partners?
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