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SMARCC2

Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Image
GO Annotations Cellular Component
  • Chromatin
  • Nucleoplasm
  • SWI/SNF Complex
  • Protein-containing Complex
  • NpBAF Complex
  • NBAF Complex
Molecular Function
  • Transcription Coactivator Activity
  • Protein Binding
  • Nucleosomal DNA Binding
  • Histone Binding
Biological Process
  • Nucleosome Disassembly
  • Chromatin Remodeling
  • Regulation Of Transcription By RNA Polymerase II
  • Nervous System Development
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription, DNA-templated
Pathways
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
  • Refractive error ( 32231278)
Interacting Genes 26 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 KRT27 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SMARCA2 SP1 SRGAP3 TAF15 TERF1
Entrez ID 6601
HPRD ID 03437
Ensembl ID ENSG00000139613
Uniprot IDs A0A024RB22 F8VXC8 Q8TAQ2
PDB IDs 6KAG 6LTH 6LTJ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025